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• W2892733021 endingPage "93" @default.
• W2892733021 startingPage "93" @default.
• W2892733021 abstract "The Chinese alligator (Alligator sinensis) is an endemic and rare species in China, and is considered to be one of the most endangered vertebrates in the world. It is known to hibernate, an energy-saving strategy against cold temperatures and food deprivation. Changes in gene expression during hibernation remain largely unknown. To understand these complex seasonal adaptive mechanisms, we performed a comprehensive survey of differential gene expression in heart, skeletal muscle, and kidney of hibernating and active Chinese alligators using RNA-Sequencing. In total, we identified 4780 genes differentially expressed between the active and hibernating periods. GO and KEGG pathway analysis indicated the likely role of these differentially expressed genes (DEGs). The upregulated DEGs in the active Chinese alligator, CSRP3, MYG and PCKGC, may maintain heart and skeletal muscle contraction, transport and storage of oxygen, and enhance the body’s metabolism, respectively. The upregulated DEGs in the dormant Chinese alligator, ADIPO, CIRBP and TMM27, may improve insulin sensitivity and glucose/lipid metabolism, protect cells against harmful effects of cold temperature and hypoxia, regulate amino acid transport and uptake, and stimulate the proliferation of islet cells and the secretion of insulin. These results provide a foundation for understanding the molecular mechanisms of the seasonal adaptation required for hibernation in Chinese alligators, as well as effective information for other non-model organisms research." @default.
• W2892733021 created "2018-10-05" @default.
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• W2892733021 date "2018-01-01" @default.
• W2892733021 modified "2023-10-16" @default.
• W2892733021 title "Insights into the seasonal adaptive mechanisms of Chinese alligators (Alligator sinensis) from transcriptomic analyses" @default.
• W2892733021 cites W1540931455 @default.
• W2892733021 cites W1973175580 @default.
• W2892733021 cites W1977035804 @default.
• W2892733021 cites W1977562391 @default.
• W2892733021 cites W1978656671 @default.
• W2892733021 cites W1979957210 @default.
• W2892733021 cites W1981509058 @default.
• W2892733021 cites W1985754099 @default.
• W2892733021 cites W1988506703 @default.
• W2892733021 cites W1999423896 @default.
• W2892733021 cites W2010911756 @default.
• W2892733021 cites W2014306428 @default.
• W2892733021 cites W2022603493 @default.
• W2892733021 cites W2033732676 @default.
• W2892733021 cites W2044493205 @default.
• W2892733021 cites W2050900577 @default.
• W2892733021 cites W2055311639 @default.
• W2892733021 cites W2060842569 @default.
• W2892733021 cites W2065025470 @default.
• W2892733021 cites W2071760290 @default.
• W2892733021 cites W2072951880 @default.
• W2892733021 cites W2073738114 @default.
• W2892733021 cites W2076397765 @default.
• W2892733021 cites W2089926698 @default.
• W2892733021 cites W2092314615 @default.
• W2892733021 cites W2095580512 @default.
• W2892733021 cites W2097114958 @default.
• W2892733021 cites W2097529842 @default.
• W2892733021 cites W2098734857 @default.
• W2892733021 cites W2104073328 @default.
• W2892733021 cites W2105106534 @default.
• W2892733021 cites W2107018762 @default.
• W2892733021 cites W2107060225 @default.
• W2892733021 cites W2114104545 @default.
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• W2892733021 cites W2119034410 @default.
• W2892733021 cites W2120949077 @default.
• W2892733021 cites W2124785544 @default.
• W2892733021 cites W2127226151 @default.
• W2892733021 cites W2134017403 @default.
• W2892733021 cites W2134526812 @default.
• W2892733021 cites W2140729960 @default.
• W2892733021 cites W2141458291 @default.
• W2892733021 cites W2141637710 @default.
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• W2892733021 cites W2147955077 @default.
• W2892733021 cites W2154431984 @default.
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• W2892733021 doi "https://doi.org/10.1071/zo18005" @default.
• W2892733021 hasPublicationYear "2018" @default.
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