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- W2892763840 abstract "The growing use of herbal dietary supplements (HDS) in the United States provides compelling evidence for risk of herbal-induced liver injury (HILI). Information on HDS products was retrieved from MedlinePlus of the U.S. National Library of Medicine and the herbal monograph of the European Medicines Agency. The hepatotoxic potential of HDS was ascertained by considering published case reports. Other relevant data were collected from governmental documents, public databases, web sources, and the literature. We collected information for 296 unique HDS products. Evidence of hepatotoxicity was reported for 67, that is 1 in 5, of these HDS products. The database revealed an apparent gender preponderance with women representing 61% of HILI cases. Culprit hepatotoxic HDS were mostly used for weight control, followed by pain and inflammation, mental stress, and mood disorders. Commonly discussed mechanistic events associated with HILI are reactive metabolites and oxidative stress, mitochondrial injury, as well as inhibition of transporters. HDS–drug interactions, causing both synergistic and antagonizing effects of drugs, were also reported for certain HDS. The database contains information for nearly 300 commonly used HDS products to provide a single-entry point for better comprehension of their impact on public health." @default.
- W2892763840 created "2018-10-05" @default.
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- W2892763840 date "2018-09-28" @default.
- W2892763840 modified "2023-10-05" @default.
- W2892763840 title "The Development of a Database for Herbal and Dietary Supplement Induced Liver Toxicity" @default.
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- W2892763840 cites W1684412556 @default.
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- W2892763840 cites W1931827816 @default.
- W2892763840 cites W1956634061 @default.
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- W2892763840 cites W1966910483 @default.
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- W2892763840 cites W1984069517 @default.
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- W2892763840 doi "https://doi.org/10.3390/ijms19102955" @default.
- W2892763840 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6213387" @default.
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