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- W2892780007 abstract "Psoriatic arthritis (PsA) is a chronic inflammatory joint disease closely associated with psoriasis. A significant advance in the management of this condition was achieved with therapeutic schemes by using tumor necrosis factor (TNF)-α inhibitors. Bone alterations, such as osteomyelitis and osteonecrosis associated with the use of a wide variety of monoclonal drugs, are known to affect the maxilla and especially the mandible. This report describes the case of a 45-year-old man with PsA treated with TNF-α inhibitors, including adalimumab, and demonstrated alterations in the mandibular bone trabeculae. As the patient's PsA was deemed refractory to treatment and control, the monoclonal antibody anti-interleukin- 17A, secukinumab (Cosentyx), was used. Psoriasis and PsA were controlled, but mandibular osteosclerosis worsened." @default.
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- W2892780007 date "2018-09-01" @default.
- W2892780007 modified "2023-09-27" @default.
- W2892780007 title "Bone Trabeculae Alterations in the Mandible of A Patient Treated with TNF-Α Inhibitors Due to Psoriatic Arthritis" @default.
- W2892780007 doi "https://doi.org/10.1016/j.oooo.2018.02.165" @default.
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