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- W2892834460 abstract "Histoplasmosis, a systemic mycosis caused by Histoplasma capsulatum, can present a variety of clinical manifestations. Disseminated histoplasmosis is a less common form of the disease, characterized by a spread of the infection to extra pulmonary sites. A 51-year-old woman was referred for investigation of a 1-month painful lesion in the mouth. The medical history revealed a previous diagnosis of Crohn's disease. An intraoral examination showed ulcerated lesions in the gingiva and labial mucosa. The diagnostic hypotheses were oral manifestation of Crohn's disease or infectious diseases. Concomitantly, a medical evaluation revealed an ulcerative lesion in the intestine (ceco). Biopsies of oral and ceco lesions were performed. A histopathological examination of both of the lesions showed chronic ulcerated inflammatory reaction. Investigation for a fungal infection yielded positive results, with the morphology confirming the diagnosis of histoplasmosis. Itraconazole therapy was initiated, and after 3 months, complete healing of the oral lesions was observed." @default.
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- W2892834460 date "2018-09-01" @default.
- W2892834460 modified "2023-10-18" @default.
- W2892834460 title "Oral Manifestation of Disseminated Histoplasmosis in A Patient with Crohn's Disease: Case Report" @default.
- W2892834460 doi "https://doi.org/10.1016/j.oooo.2018.02.438" @default.
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