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- W2892837795 abstract "The focus of treatment in MS is trending away from interventions for acute relapses, but surprisingly, the opposite is occurring in neuromyelitis optica spectrum disorder (NMOSD). Disability in NMOSD results from accumulating damage in the CNS related to individual relapses over the course of the disease. Therefore, acute interventions designed to reduce damage may preserve long-term neurologic function.1,2 The most frequent treatment approach for relapses of NMOSD comprises a schedule of high-dose steroids similar to that adopted in MS, but steroids are only partially effective. Their benefit is most apparent in blunting the extent and severity of the inflammatory response; in fact, only one-third of the patients with NMOSD revert to their previous neurologic status without additional interventions.3 Escalation to plasmapheresis after steroids in NMOSD relapses leads to a return to baseline in up to two-thirds of the patients.3" @default.
- W2892837795 created "2018-10-05" @default.
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- W2892837795 date "2018-09-26" @default.
- W2892837795 modified "2023-10-12" @default.
- W2892837795 title "Plasmapheresis for acute attacks in neuromyelitis optica spectrum disorders" @default.
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- W2892837795 doi "https://doi.org/10.1212/nxi.0000000000000510" @default.
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