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- W2892841331 abstract "Microorganisms are under constant threat by their viruses, bacteriophages (phages). In response to this pressure, they have developed multiple strategies to protect from phage infection. Mechanisms that protect microorganisms from phage infection include restriction-modification, BREX, DISARM, and CRISPR-Cas systems. However, phages have developed several mechanisms by which they can evade anti-phage defense systems. One common way to evade these systems by phages is by modifying their nucleic acids (DNA). This thesis encompasses the characterization of several CRISPR-Cas and DISARM proteins and studying the effect of phage DNA modifications on the activity of these proteins." @default.
- W2892841331 created "2018-10-05" @default.
- W2892841331 creator A5054204370 @default.
- W2892841331 date "2018-08-22" @default.
- W2892841331 modified "2023-09-25" @default.
- W2892841331 title "Access denied : A closer look at anti-phage defense mechanisms" @default.
- W2892841331 doi "https://doi.org/10.18174/449991" @default.
- W2892841331 hasPublicationYear "2018" @default.
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