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• W2892850549 abstract "So far, the only known example of deltaviruses is the hepatitis delta virus (HDV). HDV is speculated to have evolved in humans, since deltaviruses were until very recently found only in humans. Using a metatranscriptomic sequencing approach, we found a circular RNA, which resembles that of HDV in size and coding strategy, in a snake. The identification of similar deltaviruses in distantly related species other than humans indicates that the previously suggested hypotheses on the origins of deltaviruses need to be updated. It is still possible that the ancestor of deltaviruses emerged from cellular RNAs; however, it likely would have happened much earlier in evolution than previously thought. These findings open up completely new avenues in evolution and pathogenesis studies of deltaviruses." @default.
• W2892850549 created "2018-10-05" @default.
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• W2892850549 date "2019-04-30" @default.
• W2892850549 modified "2023-10-11" @default.
• W2892850549 title "Identification of a Novel Deltavirus in Boa Constrictors" @default.
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• W2892850549 doi "https://doi.org/10.1128/mbio.00014-19" @default.
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