Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892864615> ?p ?o ?g. }
- W2892864615 endingPage "776" @default.
- W2892864615 startingPage "776" @default.
- W2892864615 abstract "For biomedical applications, superparamagnetic nanoparticles (MNPs) have to be coated with a stealth layer that provides colloidal stability in biological media, long enough persistence and circulation times for reaching the expected medical aims, and anchor sites for further attachment of bioactive agents. One of such stealth molecules designed and synthesized by us, poly(polyethylene glycol methacrylate-co-acrylic acid) referred to as P(PEGMA-AA), was demonstrated to make MNPs reasonably resistant to cell internalization, and be an excellent candidate for magnetic hyperthermia treatments in addition to possessing the necessary colloidal stability under physiological conditions (Illés et al. J. Magn. Magn. Mater. 2018, 451, 710–720). In the present work, we elaborated on the molecular background of the formation of the P(PEGMA-AA)-coated MNPs, and of their remarkable colloidal stability and salt tolerance by using potentiometric acid–base titration, adsorption isotherm determination, infrared spectroscopy (FT-IR ATR), dynamic light scattering, and electrokinetic potential determination methods. The P(PEGMA-AA)@MNPs have excellent blood compatibility as demonstrated in blood sedimentation, smears, and white blood cell viability experiments. In addition, blood serum proteins formed a protein corona, protecting the particles against aggregation (found in dynamic light scattering and electrokinetic potential measurements). Our novel particles also proved to be promising candidates for MRI diagnosis, exhibiting one of the highest values of r2 relaxivity (451 mM−1s−1) found in literature." @default.
- W2892864615 created "2018-10-05" @default.
- W2892864615 creator A5026899493 @default.
- W2892864615 creator A5041970664 @default.
- W2892864615 creator A5045620902 @default.
- W2892864615 creator A5045677554 @default.
- W2892864615 creator A5070677428 @default.
- W2892864615 creator A5077322842 @default.
- W2892864615 creator A5089928622 @default.
- W2892864615 creator A5091886525 @default.
- W2892864615 date "2018-09-29" @default.
- W2892864615 modified "2023-10-09" @default.
- W2892864615 title "PEGylation of Superparamagnetic Iron Oxide Nanoparticles with Self-Organizing Polyacrylate-PEG Brushes for Contrast Enhancement in MRI Diagnosis" @default.
- W2892864615 cites W1630018437 @default.
- W2892864615 cites W1873674500 @default.
- W2892864615 cites W1965386872 @default.
- W2892864615 cites W1972063621 @default.
- W2892864615 cites W1978953799 @default.
- W2892864615 cites W1983961840 @default.
- W2892864615 cites W1985810082 @default.
- W2892864615 cites W1986995575 @default.
- W2892864615 cites W1996688719 @default.
- W2892864615 cites W1999185487 @default.
- W2892864615 cites W2008734106 @default.
- W2892864615 cites W2024182029 @default.
- W2892864615 cites W2027629680 @default.
- W2892864615 cites W2043450580 @default.
- W2892864615 cites W2048808551 @default.
- W2892864615 cites W2050955429 @default.
- W2892864615 cites W2053006484 @default.
- W2892864615 cites W2064093384 @default.
- W2892864615 cites W2067432110 @default.
- W2892864615 cites W2073608260 @default.
- W2892864615 cites W2076639767 @default.
- W2892864615 cites W2086393160 @default.
- W2892864615 cites W2096067368 @default.
- W2892864615 cites W2107910518 @default.
- W2892864615 cites W2118878458 @default.
- W2892864615 cites W2130221606 @default.
- W2892864615 cites W2143896522 @default.
- W2892864615 cites W2148358217 @default.
- W2892864615 cites W2158558808 @default.
- W2892864615 cites W2160147504 @default.
- W2892864615 cites W2337799606 @default.
- W2892864615 cites W2535503122 @default.
- W2892864615 cites W2548812626 @default.
- W2892864615 cites W2565036639 @default.
- W2892864615 cites W2592417505 @default.
- W2892864615 cites W2597931090 @default.
- W2892864615 cites W2608879075 @default.
- W2892864615 cites W2739003950 @default.
- W2892864615 cites W2757272801 @default.
- W2892864615 cites W2766149272 @default.
- W2892864615 cites W2768876774 @default.
- W2892864615 cites W2771514512 @default.
- W2892864615 cites W2788184168 @default.
- W2892864615 cites W2789674962 @default.
- W2892864615 cites W2791044421 @default.
- W2892864615 cites W3007599434 @default.
- W2892864615 cites W4300651770 @default.
- W2892864615 doi "https://doi.org/10.3390/nano8100776" @default.
- W2892864615 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6215243" @default.
- W2892864615 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30274317" @default.
- W2892864615 hasPublicationYear "2018" @default.
- W2892864615 type Work @default.
- W2892864615 sameAs 2892864615 @default.
- W2892864615 citedByCount "25" @default.
- W2892864615 countsByYear W28928646152019 @default.
- W2892864615 countsByYear W28928646152020 @default.
- W2892864615 countsByYear W28928646152021 @default.
- W2892864615 countsByYear W28928646152022 @default.
- W2892864615 countsByYear W28928646152023 @default.
- W2892864615 crossrefType "journal-article" @default.
- W2892864615 hasAuthorship W2892864615A5026899493 @default.
- W2892864615 hasAuthorship W2892864615A5041970664 @default.
- W2892864615 hasAuthorship W2892864615A5045620902 @default.
- W2892864615 hasAuthorship W2892864615A5045677554 @default.
- W2892864615 hasAuthorship W2892864615A5070677428 @default.
- W2892864615 hasAuthorship W2892864615A5077322842 @default.
- W2892864615 hasAuthorship W2892864615A5089928622 @default.
- W2892864615 hasAuthorship W2892864615A5091886525 @default.
- W2892864615 hasBestOaLocation W28928646151 @default.
- W2892864615 hasConcept C10138342 @default.
- W2892864615 hasConcept C115260700 @default.
- W2892864615 hasConcept C121332964 @default.
- W2892864615 hasConcept C127413603 @default.
- W2892864615 hasConcept C132050475 @default.
- W2892864615 hasConcept C14631669 @default.
- W2892864615 hasConcept C155672457 @default.
- W2892864615 hasConcept C15920480 @default.
- W2892864615 hasConcept C162324750 @default.
- W2892864615 hasConcept C171250308 @default.
- W2892864615 hasConcept C178790620 @default.
- W2892864615 hasConcept C185592680 @default.
- W2892864615 hasConcept C188027245 @default.
- W2892864615 hasConcept C192562407 @default.
- W2892864615 hasConcept C23792430 @default.
- W2892864615 hasConcept C27703432 @default.