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- W2892870547 abstract "Autophagy begins with the nucleation of phagophores, which then expand to give rise to the double-membrane autophagosomes. Autophagosomes ultimately fuse with lysosomes, where the cytosolic cargoes are degraded. Accumulation of autophagosomes is a hallmark of autophagy and neurodegenerative disorders including Alzheimer’s and Huntington’s disease. In recent years, the sources of autophagosome membrane have attracted a great deal of interests, even so, the membrane donors for autophagosomes are still under debate. In this review, we describe the probable sources of autophagosome membrane." @default.
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- W2892870547 date "2018-09-24" @default.
- W2892870547 modified "2023-10-15" @default.
- W2892870547 title "Origin of the Autophagosome Membrane in Mammals" @default.
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- W2892870547 doi "https://doi.org/10.1155/2018/1012789" @default.
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