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• W2892876069 abstract "Detecting reactive oxygen species (ROS) is critical for understanding the mechanisms of diseases. In this work, a convenient ratiometric fluorescent method for determination of ROS was developed basing on a nontoxic nanohybrid system which was constructed by carbon dots (CDs) and gold nanoclusters (Au NCs). The combination was prepared easily basing on self-assembly without any complex process, achieving maximum reservation of the two fluorescent properties. Thus the limit of detection (LOD) for hydrogen peroxide (H₂O₂) and hypochlorite (ClO-) was lower down to 0.1 μM after the experimental conditions were optimized. Being built to reflect H₂O₂, the test paper provided a method of convenient visual detection with double fluorescence of CDs/Au NCs. Furthermore, the biosensor was proven to be suitable for the detection of H₂O₂ and glucose (Glu) in human serum examples. The proportion of CDs and Au NCs was adjusted optionally to different color, while keeping the nanohybrid in high physiological stability and excellent biocompatibility. The excellent performance of this ratiometric biosensor is expected to facilitate further development of rapid and high-throughput detection of ROS." @default.
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• W2892876069 date "2017-11-01" @default.
• W2892876069 modified "2023-09-27" @default.
• W2892876069 title "A Dual-Emission Nanohybrid of Gold Nanoclusters and Carbon Dots for Ratiometric Fluorescence Detection of Reactive Oxygen Species and Glucose" @default.
• W2892876069 doi "https://doi.org/10.1166/jbn.2017.2432" @default.
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