FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892884584> ?p ?o ?g. }

• W2892884584 abstract "Human adenoviruses are common causes of community-acquired respiratory tract and enteric infections. Severe disseminated infections with high mortality rates may be seen in immunocompromised individuals. An accurate and cost-effective quantitative assay is essential not only for laboratory diagnosis of adenoviral infections, but also for monitoring of response to antiviral treatment. The diagnostic performance of an in-house quantitative polymerase chain reaction assay was compared to a commercial system.The analytical sensitivity, specificity, linearity, precision and accuracy of an in-house adenovirus quantitative polymerase chain reaction assay were evaluated against the RealStar® Adenovirus PCR Kit (Altona Diagnostics GmbH, Hamburg, Germany), using 122 clinical specimens and 18 proficiency testing samples.Linear regression analysis of the quantitative results by the in-house assay showed the dynamic range from 2.60 to 9 log10 (plasma) and 2.94 to 9 log10 (viral transport medium) copies/mL, with the coefficient of determination (R2) of 0.996 and 0.998, respectively. A dilution series demonstrated the limits of detection and lower limits of quantification for plasma were 2.06 log10 and 2.60 log10 copies/mL and those for viral transport medium were 2.31 log10 and 2.94 log10 copies/mL respectively. The precision of the in-house assay was highly reproducible among runs with coefficients of variance ranging from 0.07 to 3.21% for plasma and 0.17% to 2.11% for viral transport medium. A comparison of 52 matched samples showed an excellent correlation between the quantitative viral loads measured by the in-house assay and the RealStar® Adenovirus PCR Kit (R2 = 0.984), with an average bias of - 0.16 log10 copies/mL.The in-house adenovirus assay is a sensitive and reliable assay with lower cost for the detection and quantification of adenoviral DNA when compared to the RealStar® Adenovirus PCR Kit." @default.
• W2892884584 created "2018-10-05" @default.
• W2892884584 creator A5001632717 @default.
• W2892884584 creator A5008625579 @default.
• W2892884584 creator A5019585842 @default.
• W2892884584 creator A5021700176 @default.
• W2892884584 creator A5030565867 @default.
• W2892884584 creator A5038137571 @default.
• W2892884584 creator A5041469482 @default.
• W2892884584 creator A5056994730 @default.
• W2892884584 creator A5059735518 @default.
• W2892884584 creator A5060485769 @default.
• W2892884584 creator A5061410042 @default.
• W2892884584 creator A5077326959 @default.
• W2892884584 date "2018-09-27" @default.
• W2892884584 modified "2023-10-14" @default.
• W2892884584 title "Comparative evaluation of a laboratory-developed real-time PCR assay and RealStar® Adenovirus PCR Kit for quantitative detection of human adenovirus" @default.
• W2892884584 cites W1497564698 @default.
• W2892884584 cites W1601616737 @default.
• W2892884584 cites W1928200073 @default.
• W2892884584 cites W1970339303 @default.
• W2892884584 cites W1976868395 @default.
• W2892884584 cites W1982041503 @default.
• W2892884584 cites W1985226754 @default.
• W2892884584 cites W1990617809 @default.
• W2892884584 cites W1991533086 @default.
• W2892884584 cites W1999220811 @default.
• W2892884584 cites W2007618921 @default.
• W2892884584 cites W2011068991 @default.
• W2892884584 cites W2056381325 @default.
• W2892884584 cites W2057917006 @default.
• W2892884584 cites W2077349574 @default.
• W2892884584 cites W2093204006 @default.
• W2892884584 cites W2096278562 @default.
• W2892884584 cites W2128219656 @default.
• W2892884584 cites W2145402878 @default.
• W2892884584 cites W2160004262 @default.
• W2892884584 cites W2166978710 @default.
• W2892884584 cites W2168089972 @default.
• W2892884584 cites W2312460135 @default.
• W2892884584 cites W2315773537 @default.
• W2892884584 cites W2404418080 @default.
• W2892884584 cites W2464314588 @default.
• W2892884584 cites W2539205562 @default.
• W2892884584 cites W2611127149 @default.
• W2892884584 cites W2770860018 @default.
• W2892884584 doi "https://doi.org/10.1186/s12985-018-1059-7" @default.
• W2892884584 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6161464" @default.
• W2892884584 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30261891" @default.
• W2892884584 hasPublicationYear "2018" @default.
• W2892884584 type Work @default.
• W2892884584 sameAs 2892884584 @default.
• W2892884584 citedByCount "11" @default.
• W2892884584 countsByYear W28928845842020 @default.
• W2892884584 countsByYear W28928845842021 @default.
• W2892884584 countsByYear W28928845842022 @default.
• W2892884584 countsByYear W28928845842023 @default.
• W2892884584 crossrefType "journal-article" @default.
• W2892884584 hasAuthorship W2892884584A5001632717 @default.
• W2892884584 hasAuthorship W2892884584A5008625579 @default.
• W2892884584 hasAuthorship W2892884584A5019585842 @default.
• W2892884584 hasAuthorship W2892884584A5021700176 @default.
• W2892884584 hasAuthorship W2892884584A5030565867 @default.
• W2892884584 hasAuthorship W2892884584A5038137571 @default.
• W2892884584 hasAuthorship W2892884584A5041469482 @default.
• W2892884584 hasAuthorship W2892884584A5056994730 @default.
• W2892884584 hasAuthorship W2892884584A5059735518 @default.
• W2892884584 hasAuthorship W2892884584A5060485769 @default.
• W2892884584 hasAuthorship W2892884584A5061410042 @default.
• W2892884584 hasAuthorship W2892884584A5077326959 @default.
• W2892884584 hasBestOaLocation W28928845841 @default.
• W2892884584 hasConcept C104317684 @default.
• W2892884584 hasConcept C142462285 @default.
• W2892884584 hasConcept C153911025 @default.
• W2892884584 hasConcept C159047783 @default.
• W2892884584 hasConcept C2522874641 @default.
• W2892884584 hasConcept C48023723 @default.
• W2892884584 hasConcept C49105822 @default.
• W2892884584 hasConcept C55493867 @default.
• W2892884584 hasConcept C86803240 @default.
• W2892884584 hasConceptScore W2892884584C104317684 @default.
• W2892884584 hasConceptScore W2892884584C142462285 @default.
• W2892884584 hasConceptScore W2892884584C153911025 @default.
• W2892884584 hasConceptScore W2892884584C159047783 @default.
• W2892884584 hasConceptScore W2892884584C2522874641 @default.
• W2892884584 hasConceptScore W2892884584C48023723 @default.
• W2892884584 hasConceptScore W2892884584C49105822 @default.
• W2892884584 hasConceptScore W2892884584C55493867 @default.
• W2892884584 hasConceptScore W2892884584C86803240 @default.
• W2892884584 hasIssue "1" @default.
• W2892884584 hasLocation W28928845841 @default.
• W2892884584 hasLocation W28928845842 @default.
• W2892884584 hasLocation W28928845843 @default.
• W2892884584 hasLocation W28928845844 @default.
• W2892884584 hasOpenAccess W2892884584 @default.
• W2892884584 hasPrimaryLocation W28928845841 @default.
• W2892884584 hasRelatedWork W1938450991 @default.
• W2892884584 hasRelatedWork W2016082374 @default.
• W2892884584 hasRelatedWork W2054848430 @default.
• W2892884584 hasRelatedWork W2056420846 @default.

• next