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- W2892889979 abstract "In cancer patients, antithrombotic medications (i.e. anticoagulation or antiplatelet therapy) are frequently prescribed for prior or new indications such as venous thromboembolism or stoke prevention in atrial fibrillation. Balancing the risks of bleeding and thrombosis during periods of thrombocytopenia represents a significant challenge. Management is informed mainly by expert opinion and several recent retrospective studies on venous thromboembolism. The main management options include no change, temporarily withholding antithrombotic therapy, reducing dose, changing the regimen, and increasing the platelet transfusion threshold. Important recent advances in knowledge include the prognostic importance and apparent safety of aspirin in acute myocardial infarction and thrombocytopenia and data suggesting a low risk of recurrent venous thromboembolism in autologous stem cell transplantation patients who had anticoagulation withheld. This paper will review the literature on antithrombotic medication in thrombocytopenic patients with cancer. The significant knowledge gaps will be summarized and considerations for practice and research will be provided." @default.
- W2892889979 created "2018-10-05" @default.
- W2892889979 creator A5032570763 @default.
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- W2892889979 creator A5039403992 @default.
- W2892889979 creator A5039927165 @default.
- W2892889979 creator A5046708642 @default.
- W2892889979 date "2018-12-01" @default.
- W2892889979 modified "2023-10-17" @default.
- W2892889979 title "Antithrombotic medication in cancer-associated thrombocytopenia: Current evidence and knowledge gaps" @default.
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