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• W2892915741 endingPage "HEP09" @default.
• W2892915741 startingPage "HEP09" @default.
• W2892915741 abstract "The hormone secretion in pancreatic neuroendocrine tumors (pNET) causes an important interference in patients' quality of life. We present two cases of pNET metastatic to the liver (a pancreatic endocrine carcinoma with a severe hormonal syndrome and an insulinoma with severe crisis of hypoglycemia and coma) refractory to conventional treatments, which were finally solved with selective internal radiation therapy (SIRT), a nonstandard level 1 therapy. We show two examples of an excellent control of symptoms together with a long survival after treatment with SIRT. The evidence supporting the use of this therapy is level 2. Our case reports strongly support the use of SIRT for the severe clinical syndrome in pNET metastatic to the liver and refractory to somatostatin analogs." @default.
• W2892915741 created "2018-10-05" @default.
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• W2892915741 date "2018-04-01" @default.
• W2892915741 modified "2023-09-27" @default.
• W2892915741 title "Selective internal radiation therapy: an effective treatment for hormonal syndromes in pancreatic neuroendocrine tumors" @default.
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• W2892915741 doi "https://doi.org/10.2217/hep-2017-0025" @default.
• W2892915741 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6613041" @default.
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