FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892952367> ?p ?o ?g. }

• W2892952367 endingPage "331" @default.
• W2892952367 startingPage "324" @default.
• W2892952367 abstract "Abstract Shenmai injection (SMI) is increasingly used in tumor combination therapy, devoting to enhancing anti‐tumor effects and reducing the toxicity of chemotherapy drugs. This study aimed to explore the role of SMI in papillary thyroid carcinoma (PTC) treatment. Flow cytometry was used to examine Treg cells percentage in CD4 + T cells. The expression of RNA and protein was analyzed by quantitative real‐time polymerase chain reaction (qRT‐PCR) and Western blot, respectively. Inducers were used to stimulate CD4 + T cells to differentiate into Treg cells. The interaction between miR‐103 and G protein‐coupled estrogen receptor 1 (GPER1) was confirmed with the dual luciferase assays. Cell transfection and recombinant plasmids were used to achieve endogenous expression. Compared with patients not treated with 131 I, the Treg cells percentage and Foxp3 expression were clearly increased in patients with 131 I radiotherapy, just the opposite in SMI combination therapy. SMI inhibited the differentiation of CD4 + T cells into Treg cells. Aberrant expression of miR‐103 and GPER1 induced by 131 I was reversed by SMI and 131 I combination therapy. GPER1 was negatively regulated by miR‐103 and SMI inhibits the differentiation of CD4 + T cells into Treg cells via miR‐103/GPER1 axis, which improves the postoperative immunological function of PTC patients with 131 I radiotherapy." @default.
• W2892952367 created "2018-10-05" @default.
• W2892952367 creator A5026605210 @default.
• W2892952367 creator A5038930096 @default.
• W2892952367 creator A5075662908 @default.
• W2892952367 date "2018-09-29" @default.
• W2892952367 modified "2023-09-30" @default.
• W2892952367 title "Shenmai injection improves the postoperative immune function of papillary thyroid carcinoma patients by inhibiting differentiation into Treg cells via miR-103/GPER1 axis" @default.
• W2892952367 cites W141445146 @default.
• W2892952367 cites W1540717160 @default.
• W2892952367 cites W1976661673 @default.
• W2892952367 cites W1978346362 @default.
• W2892952367 cites W1981467972 @default.
• W2892952367 cites W1991261234 @default.
• W2892952367 cites W1992893061 @default.
• W2892952367 cites W2004512161 @default.
• W2892952367 cites W2008821525 @default.
• W2892952367 cites W2009183851 @default.
• W2892952367 cites W2027744584 @default.
• W2892952367 cites W2028080080 @default.
• W2892952367 cites W2030612376 @default.
• W2892952367 cites W2041251477 @default.
• W2892952367 cites W2047355346 @default.
• W2892952367 cites W2049352712 @default.
• W2892952367 cites W2066472069 @default.
• W2892952367 cites W2072217210 @default.
• W2892952367 cites W2076196135 @default.
• W2892952367 cites W2079572580 @default.
• W2892952367 cites W2081540476 @default.
• W2892952367 cites W2089715072 @default.
• W2892952367 cites W2102650038 @default.
• W2892952367 cites W2122313273 @default.
• W2892952367 cites W2144198062 @default.
• W2892952367 cites W2147331081 @default.
• W2892952367 cites W2153659956 @default.
• W2892952367 cites W2160270310 @default.
• W2892952367 cites W2169083371 @default.
• W2892952367 cites W2553832532 @default.
• W2892952367 cites W2569636412 @default.
• W2892952367 cites W2943697700 @default.
• W2892952367 doi "https://doi.org/10.1002/ddr.21459" @default.
• W2892952367 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30267584" @default.
• W2892952367 hasPublicationYear "2018" @default.
• W2892952367 type Work @default.
• W2892952367 sameAs 2892952367 @default.
• W2892952367 citedByCount "20" @default.
• W2892952367 countsByYear W28929523672020 @default.
• W2892952367 countsByYear W28929523672021 @default.
• W2892952367 countsByYear W28929523672022 @default.
• W2892952367 countsByYear W28929523672023 @default.
• W2892952367 crossrefType "journal-article" @default.
• W2892952367 hasAuthorship W2892952367A5026605210 @default.
• W2892952367 hasAuthorship W2892952367A5038930096 @default.
• W2892952367 hasAuthorship W2892952367A5075662908 @default.
• W2892952367 hasConcept C104317684 @default.
• W2892952367 hasConcept C111335760 @default.
• W2892952367 hasConcept C126322002 @default.
• W2892952367 hasConcept C134018914 @default.
• W2892952367 hasConcept C170493617 @default.
• W2892952367 hasConcept C203014093 @default.
• W2892952367 hasConcept C2776415932 @default.
• W2892952367 hasConcept C2779727006 @default.
• W2892952367 hasConcept C2993294228 @default.
• W2892952367 hasConcept C502942594 @default.
• W2892952367 hasConcept C526584372 @default.
• W2892952367 hasConcept C54009773 @default.
• W2892952367 hasConcept C54355233 @default.
• W2892952367 hasConcept C553184892 @default.
• W2892952367 hasConcept C55493867 @default.
• W2892952367 hasConcept C71924100 @default.
• W2892952367 hasConcept C81885089 @default.
• W2892952367 hasConcept C86803240 @default.
• W2892952367 hasConcept C8891405 @default.
• W2892952367 hasConceptScore W2892952367C104317684 @default.
• W2892952367 hasConceptScore W2892952367C111335760 @default.
• W2892952367 hasConceptScore W2892952367C126322002 @default.
• W2892952367 hasConceptScore W2892952367C134018914 @default.
• W2892952367 hasConceptScore W2892952367C170493617 @default.
• W2892952367 hasConceptScore W2892952367C203014093 @default.
• W2892952367 hasConceptScore W2892952367C2776415932 @default.
• W2892952367 hasConceptScore W2892952367C2779727006 @default.
• W2892952367 hasConceptScore W2892952367C2993294228 @default.
• W2892952367 hasConceptScore W2892952367C502942594 @default.
• W2892952367 hasConceptScore W2892952367C526584372 @default.
• W2892952367 hasConceptScore W2892952367C54009773 @default.
• W2892952367 hasConceptScore W2892952367C54355233 @default.
• W2892952367 hasConceptScore W2892952367C553184892 @default.
• W2892952367 hasConceptScore W2892952367C55493867 @default.
• W2892952367 hasConceptScore W2892952367C71924100 @default.
• W2892952367 hasConceptScore W2892952367C81885089 @default.
• W2892952367 hasConceptScore W2892952367C86803240 @default.
• W2892952367 hasConceptScore W2892952367C8891405 @default.
• W2892952367 hasIssue "7" @default.
• W2892952367 hasLocation W28929523671 @default.
• W2892952367 hasLocation W28929523672 @default.
• W2892952367 hasOpenAccess W2892952367 @default.
• W2892952367 hasPrimaryLocation W28929523671 @default.
• W2892952367 hasRelatedWork W1981968121 @default.

• next