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- W2892961546 abstract "Autotetraploid fish (4 n = 200, abbreviated as 4 n RR), which reach sexual maturity at 1 year of age, were derived from the whole genome duplication of red crucian carp Carassius auratus red var. (RCC; 2 n = 100) and possess four sets of chromosomes from RCC. The histological features of the gonads showed that the RCC and 4 n RR both possessed normal gonadal structure and could arrive at maturation. To understand the expression characteristics of genes related to reproductive development in the autotetraploid fish, we analysed the nucleotide sequence and expression characteristics of the gnrh 2, gthb and gthr genes, which are the pivotal genes of the hypothalamic–pituitary–gonadal (HPG) axis. We found that the gnrh 2, gthb and gthr genes in 4 n RR share remarkable homology with RCC, but there were obvious differences in expression levels between 4 n RR and RCC. These results demonstrate that autotetraploidization can lead to gene expression changes. This study provides insights into the molecular mechanism underlying the reproductive development of autotetraploid fish and is expected to be of great significance for subsequent research on polyploidization." @default.
- W2892961546 created "2018-10-05" @default.
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- W2892961546 date "2018-12-01" @default.
- W2892961546 modified "2023-09-27" @default.
- W2892961546 title "Differential expression of HPG‐axis genes in autotetraploids derived from red crucian carp <scp> <i>Carassius auratus</i> </scp> red var., ♀ × blunt snout bream <scp> <i>Megalobrama amblycephala</i> </scp> <i>,</i> ♂" @default.
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- W2892961546 doi "https://doi.org/10.1111/jfb.13818" @default.
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