FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2892973267> ?p ?o ?g. }

• W2892973267 endingPage "110" @default.
• W2892973267 startingPage "103" @default.
• W2892973267 abstract "Lung metastases are common in pediatric thyroid cancer (TC). We present an analysis of a series of lung metastases in pediatric TC. Data from 20 patients (16 females, 4 males; median age, 14.5 years; range 10 to 18 years) were analyzed. The tumors included differentiated TC in 19 patients and poorly differentiated TC in 1 patient. Lung metastasis presented with three distinct radiological patterns: lung uptake on diagnostic radioactive iodine whole body scan (DxWBS) only in 3 patients (15%); lung uptake on DxWBS and CT scan as micrometastases (≤1 cm) in 16 patients (80%); and lung uptake on DxWBS and CT scan as macrometastases (>1 cm) in 1 patient (5%). Iodine-131 therapies were administered to all patients (median, three; range one to eight) with a median cumulative administered activity of 317.5 mCi (range, 109 to 682 mCi). None of the patients achieved a complete response but the biochemical response was substantial. During a median follow-up period of 8.2 years (range, 0.75 to 16.3 years), 1 patient (5%) died, 1 patient (5%) had a biochemically incomplete response, 2 patients (10%) had an indeterminate response, 1 patient (5%) had progressive structural disease, and 14 patients (70%) had stable structural disease. Mutational testing of 10 of 20 tumors revealed only two PIK3CA mutations in a single tumor. Lung metastases are common in pediatric TC and present most frequently with bilateral radioiodine-avid micrometastases. Known single point mutations in adult TC are rare in pediatric TC. The biochemical response to iodine-131 can be substantial but resolution of structural abnormalities is rare." @default.
• W2892973267 created "2018-10-05" @default.
• W2892973267 creator A5006485028 @default.
• W2892973267 creator A5024057082 @default.
• W2892973267 creator A5031473715 @default.
• W2892973267 creator A5041324218 @default.
• W2892973267 creator A5051981478 @default.
• W2892973267 creator A5067099542 @default.
• W2892973267 creator A5069842414 @default.
• W2892973267 creator A5075970031 @default.
• W2892973267 creator A5090489998 @default.
• W2892973267 date "2018-09-28" @default.
• W2892973267 modified "2023-10-17" @default.
• W2892973267 title "Lung Metastasis in Pediatric Thyroid Cancer: Radiological Pattern, Molecular Genetics, Response to Therapy, and Outcome" @default.
• W2892973267 cites W1848939527 @default.
• W2892973267 cites W1941653842 @default.
• W2892973267 cites W1990713861 @default.
• W2892973267 cites W1996797251 @default.
• W2892973267 cites W2000251705 @default.
• W2892973267 cites W2033582657 @default.
• W2892973267 cites W2040165720 @default.
• W2892973267 cites W2040642592 @default.
• W2892973267 cites W2048252958 @default.
• W2892973267 cites W2054255592 @default.
• W2892973267 cites W2063906976 @default.
• W2892973267 cites W2080705795 @default.
• W2892973267 cites W2099982919 @default.
• W2892973267 cites W2103523670 @default.
• W2892973267 cites W2105132224 @default.
• W2892973267 cites W2118986295 @default.
• W2892973267 cites W2127368054 @default.
• W2892973267 cites W2127959803 @default.
• W2892973267 cites W2138732704 @default.
• W2892973267 cites W2143002495 @default.
• W2892973267 cites W2145150141 @default.
• W2892973267 cites W2154071623 @default.
• W2892973267 cites W2169961966 @default.
• W2892973267 cites W2171379946 @default.
• W2892973267 cites W2190935753 @default.
• W2892973267 cites W2225849677 @default.
• W2892973267 cites W2314815360 @default.
• W2892973267 cites W2464424134 @default.
• W2892973267 cites W2603577764 @default.
• W2892973267 cites W2611699884 @default.
• W2892973267 doi "https://doi.org/10.1210/jc.2018-01690" @default.
• W2892973267 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30272236" @default.
• W2892973267 hasPublicationYear "2018" @default.
• W2892973267 type Work @default.
• W2892973267 sameAs 2892973267 @default.
• W2892973267 citedByCount "24" @default.
• W2892973267 countsByYear W28929732672020 @default.
• W2892973267 countsByYear W28929732672021 @default.
• W2892973267 countsByYear W28929732672022 @default.
• W2892973267 countsByYear W28929732672023 @default.
• W2892973267 crossrefType "journal-article" @default.
• W2892973267 hasAuthorship W2892973267A5006485028 @default.
• W2892973267 hasAuthorship W2892973267A5024057082 @default.
• W2892973267 hasAuthorship W2892973267A5031473715 @default.
• W2892973267 hasAuthorship W2892973267A5041324218 @default.
• W2892973267 hasAuthorship W2892973267A5051981478 @default.
• W2892973267 hasAuthorship W2892973267A5067099542 @default.
• W2892973267 hasAuthorship W2892973267A5069842414 @default.
• W2892973267 hasAuthorship W2892973267A5075970031 @default.
• W2892973267 hasAuthorship W2892973267A5090489998 @default.
• W2892973267 hasBestOaLocation W28929732671 @default.
• W2892973267 hasConcept C121608353 @default.
• W2892973267 hasConcept C126322002 @default.
• W2892973267 hasConcept C126838900 @default.
• W2892973267 hasConcept C142724271 @default.
• W2892973267 hasConcept C143998085 @default.
• W2892973267 hasConcept C190892606 @default.
• W2892973267 hasConcept C2776256026 @default.
• W2892973267 hasConcept C2777714996 @default.
• W2892973267 hasConcept C2778822529 @default.
• W2892973267 hasConcept C2779013556 @default.
• W2892973267 hasConcept C2779134260 @default.
• W2892973267 hasConcept C2779761222 @default.
• W2892973267 hasConcept C526584372 @default.
• W2892973267 hasConcept C71924100 @default.
• W2892973267 hasConcept C90924648 @default.
• W2892973267 hasConceptScore W2892973267C121608353 @default.
• W2892973267 hasConceptScore W2892973267C126322002 @default.
• W2892973267 hasConceptScore W2892973267C126838900 @default.
• W2892973267 hasConceptScore W2892973267C142724271 @default.
• W2892973267 hasConceptScore W2892973267C143998085 @default.
• W2892973267 hasConceptScore W2892973267C190892606 @default.
• W2892973267 hasConceptScore W2892973267C2776256026 @default.
• W2892973267 hasConceptScore W2892973267C2777714996 @default.
• W2892973267 hasConceptScore W2892973267C2778822529 @default.
• W2892973267 hasConceptScore W2892973267C2779013556 @default.
• W2892973267 hasConceptScore W2892973267C2779134260 @default.
• W2892973267 hasConceptScore W2892973267C2779761222 @default.
• W2892973267 hasConceptScore W2892973267C526584372 @default.
• W2892973267 hasConceptScore W2892973267C71924100 @default.
• W2892973267 hasConceptScore W2892973267C90924648 @default.
• W2892973267 hasIssue "1" @default.
• W2892973267 hasLocation W28929732671 @default.
• W2892973267 hasLocation W28929732672 @default.

• next