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• W2892980534 abstract "The primary goal of this work is to develop an efficient Monte-Carlo simulation of diffusion-weighted signal in complex cellular structures, such as astrocytes, directly derived from confocal microscopy. In this study, we first use an octree structure for spatial decomposition of surface meshes. Octree structure and radius-search algorithm help to quickly identify the faces that particles can possibly encounter during the next time step, thus speeding up the Monte-Carlo simulation. Furthermore, we propose to use a three-dimensional binary marker to describe the complex cellular structure and optimize the particle trajectory simulation. Finally, a GPU-based version of these two approaches is implemented for more efficient modeling. It is shown that the GPU-based binary marker approach yields unparalleled performance, opening up new possibilities to better understand intracellular diffusion, validate diffusion models, and create dictionaries of intracellular diffusion signatures." @default.
• W2892980534 created "2018-10-05" @default.
• W2892980534 creator A5005512319 @default.
• W2892980534 creator A5021504897 @default.
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• W2892980534 date "2018-11-01" @default.
• W2892980534 modified "2023-10-18" @default.
• W2892980534 title "Efficient GPU-based Monte-Carlo simulation of diffusion in real astrocytes reconstructed from confocal microscopy" @default.
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• W2892980534 doi "https://doi.org/10.1016/j.jmr.2018.09.013" @default.
• W2892980534 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30296779" @default.
• W2892980534 hasPublicationYear "2018" @default.
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