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- W2893043767 abstract "Poly(lactic-co-glycolic acid)/Ag/ZnO nanorods coating were successfully prepared on the surface of Ti metallic implants using a hydrothermal method and subsequent spin-coating of mixtures of poly(lactic-co-glycolic acid) and silver nanoparticles. The poly(lactic-co-glycolic acid)/Ag/ZnO nanorods coating exhibited excellent antibacterial efficacy of over 96% against both Staphylococcus aureus and Escherichia coli when the initial content of Ag nanoparticles was over 3 wt%. In addition, the release of both silver and zinc could last for over a hundred days due to the enwrapping of poly(lactic-co-glycolic acid). Proliferation of mouse calvarial cells exhibited minimal cytotoxicity on the poly(lactic-co-glycolic acid)/Ag/ZnO coating with an initial content of Ag nanoparticles of 1 wt% and 3 wt%, while it inhibited cell proliferation once this value was increased to 6 wt%. The results revealed that this poly(lactic-co-glycolic acid)/Ag/ZnO composite could provide a long-lasting antibacterial approach and good cytocompatibility, thus exhibiting considerable potential for biomedical application in orthopedic and dental implants with excellent self-antibacterial activity and good biocompatibility." @default.
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- W2893043767 date "2018-10-01" @default.
- W2893043767 modified "2023-09-25" @default.
- W2893043767 title "Antibacterial activity of zinc oxide and copper oxide nanoparticles against Gram-positive and Gram-negative bacterial strains ss" @default.
- W2893043767 doi "https://doi.org/10.1016/j.nbt.2018.05.1263" @default.
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