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- W2893044900 abstract "Leprosy is a chronic infectious disease caused by intracellular Mycobacterium leprae. Although specific oral lesions are uncommon, they may occur in patients with advanced stages of lepromatous leprosy (LL). We describe the clinicopathologic data of 13 cases of leprosy with oral manifestations. All cases exhibited LL with extensive cutaneous involvement. Oral examination revealed different patterns of lesions, including red patches, papules, and nodes, as well as ulcers on the hard palate and tongue. Biopsy of the oral lesions demonstrated epithelial hyperplasia and connective tissue composed of a dense, patchy lymphohistiocytic infiltrate, containing numerous foamy macrophages with intact bacilli; a diagnosis of leprosy was made. Patients were started on treatment with multidrug therapy for multibacillary leprosy; 6 patients have completed the treatment, and 7 are still undergoing treatment. These cases demonstrate that although rare, leprosy can affect the oral mucosa, underscoring the importance of its evaluation during disease diagnosis." @default.
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- W2893044900 date "2018-09-01" @default.
- W2893044900 modified "2023-10-16" @default.
- W2893044900 title "Oral Manifestation of Leprosy: A Clinicopathologic Study of 13 Cases" @default.
- W2893044900 doi "https://doi.org/10.1016/j.oooo.2018.02.033" @default.
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