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• W2893062905 endingPage "515" @default.
• W2893062905 startingPage "511" @default.
• W2893062905 abstract "Newts and salamanders, both urodele amphibians, are the only vertebrates with tremendous regenerative potency throughout their lifetime. In contrast to the limited regenerative potential of most mammals, including humans, they can regenerate an entire limb after amputation and many other structures of their bodies, whereas humans mainly respond to injury by the formation of a scar. The intention of plastic surgery is to restore function of injured body parts, with the highest principle to replace “like with like.” Despite tremendous improvements in surgical techniques over the last century, the remaining drawbacks include the availability of autologous tissue for transfer to restore extensive tissue loss. Here, some regenerative features of the urodeles are reviewed, in particular wound healing, nerve and limb regeneration, and their potential impact for reconstructive surgery are discussed. With a detailed molecular and cellular understanding of the urodele regeneration processes in combination with recent advances in tissue engineering, new perspectives for plastic surgery and especially improvements in regards to tissue regeneration are opened." @default.
• W2893062905 created "2018-10-05" @default.
• W2893062905 creator A5014297811 @default.
• W2893062905 creator A5071815402 @default.
• W2893062905 date "2018-11-01" @default.
• W2893062905 modified "2023-09-25" @default.
• W2893062905 title "The Regenerative Capability of the Urodele Amphibians and Its Potential for Plastic Surgery" @default.
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• W2893062905 doi "https://doi.org/10.1097/sap.0000000000001619" @default.
• W2893062905 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30247194" @default.
• W2893062905 hasPublicationYear "2018" @default.
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