Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893065705> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2893065705 endingPage "120" @default.
- W2893065705 startingPage "116" @default.
- W2893065705 abstract "Studies have found increased expression of IL-23 in inflamed and non-inflamed mucosa of patients with ulcerative colitis (UC). We hypothesized that serum interleukin-23 as a non-invasive test has a role in pathogenesis of ulcerative colitis disease and correlates with the disease severity.Forty patients with biopsy proven ulcerative colitis, recruited from Ain Shams University hospitals were included. Forty healthy subjects matched in age and gender were also included in the study as a control group. Serum IL-23 level was quantified using quantitative ELISA technique (Enzyme linked Immunosorbent Assay).Patients with UC had higher level of interleukin 23 (234.5 ± 161 pg/mL) compared to control subjects (54.2 ± 15 pg/mL) and the level of IL-23 correlated with the disease severity. Cut off value of IL-23 at 68 pg/mL was the best to differentiate between cases and control subjects. Receiver operating characteristic curve (ROC) revealed that the best cut off for IL-23 to detect mild cases of ulcerative colitis was at105 pg/mL, to detect moderate cases at 200 pg/mL and to detect severe cases was at 270 pg/mL with sensitivity 80% to mild cases, 60% to moderate cases and 81% to severe cases.Our findings confirm the suggestion that IL-23 level measurement may be of value as a non-invasive test in the diagnosis and disease severity assessment in patients with UC." @default.
- W2893065705 created "2018-10-05" @default.
- W2893065705 creator A5049409351 @default.
- W2893065705 creator A5064439834 @default.
- W2893065705 creator A5067841930 @default.
- W2893065705 creator A5076537795 @default.
- W2893065705 creator A5082447969 @default.
- W2893065705 creator A5091368027 @default.
- W2893065705 date "2018-09-01" @default.
- W2893065705 modified "2023-10-16" @default.
- W2893065705 title "Evaluation of interleukin 23 (IL-23) as a non-invasive test of disease severity in patients with ulcerative colitis" @default.
- W2893065705 cites W1596173029 @default.
- W2893065705 cites W1671928120 @default.
- W2893065705 cites W1980055161 @default.
- W2893065705 cites W1981714996 @default.
- W2893065705 cites W2025297401 @default.
- W2893065705 cites W2047363745 @default.
- W2893065705 cites W2048254951 @default.
- W2893065705 cites W2061154423 @default.
- W2893065705 cites W2064550435 @default.
- W2893065705 cites W2074003071 @default.
- W2893065705 cites W2076889715 @default.
- W2893065705 cites W2094730640 @default.
- W2893065705 cites W2120522488 @default.
- W2893065705 cites W2133765154 @default.
- W2893065705 cites W2136474420 @default.
- W2893065705 cites W2140887143 @default.
- W2893065705 cites W2143625465 @default.
- W2893065705 cites W2152748900 @default.
- W2893065705 cites W2166356293 @default.
- W2893065705 cites W2167264906 @default.
- W2893065705 cites W2321205867 @default.
- W2893065705 cites W4238322028 @default.
- W2893065705 cites W7272284 @default.
- W2893065705 doi "https://doi.org/10.1016/j.ajg.2018.09.003" @default.
- W2893065705 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30268427" @default.
- W2893065705 hasPublicationYear "2018" @default.
- W2893065705 type Work @default.
- W2893065705 sameAs 2893065705 @default.
- W2893065705 citedByCount "6" @default.
- W2893065705 countsByYear W28930657052019 @default.
- W2893065705 countsByYear W28930657052020 @default.
- W2893065705 countsByYear W28930657052021 @default.
- W2893065705 countsByYear W28930657052023 @default.
- W2893065705 crossrefType "journal-article" @default.
- W2893065705 hasAuthorship W2893065705A5049409351 @default.
- W2893065705 hasAuthorship W2893065705A5064439834 @default.
- W2893065705 hasAuthorship W2893065705A5067841930 @default.
- W2893065705 hasAuthorship W2893065705A5076537795 @default.
- W2893065705 hasAuthorship W2893065705A5082447969 @default.
- W2893065705 hasAuthorship W2893065705A5091368027 @default.
- W2893065705 hasConcept C126322002 @default.
- W2893065705 hasConcept C146304588 @default.
- W2893065705 hasConcept C2775862500 @default.
- W2893065705 hasConcept C2778260677 @default.
- W2893065705 hasConcept C2779134260 @default.
- W2893065705 hasConcept C2780479503 @default.
- W2893065705 hasConcept C2780942790 @default.
- W2893065705 hasConcept C58471807 @default.
- W2893065705 hasConcept C71924100 @default.
- W2893065705 hasConcept C90924648 @default.
- W2893065705 hasConceptScore W2893065705C126322002 @default.
- W2893065705 hasConceptScore W2893065705C146304588 @default.
- W2893065705 hasConceptScore W2893065705C2775862500 @default.
- W2893065705 hasConceptScore W2893065705C2778260677 @default.
- W2893065705 hasConceptScore W2893065705C2779134260 @default.
- W2893065705 hasConceptScore W2893065705C2780479503 @default.
- W2893065705 hasConceptScore W2893065705C2780942790 @default.
- W2893065705 hasConceptScore W2893065705C58471807 @default.
- W2893065705 hasConceptScore W2893065705C71924100 @default.
- W2893065705 hasConceptScore W2893065705C90924648 @default.
- W2893065705 hasIssue "3" @default.
- W2893065705 hasLocation W28930657051 @default.
- W2893065705 hasLocation W28930657052 @default.
- W2893065705 hasOpenAccess W2893065705 @default.
- W2893065705 hasPrimaryLocation W28930657051 @default.
- W2893065705 hasRelatedWork W1596258860 @default.
- W2893065705 hasRelatedWork W2055638945 @default.
- W2893065705 hasRelatedWork W2105447106 @default.
- W2893065705 hasRelatedWork W2377889993 @default.
- W2893065705 hasRelatedWork W2394548049 @default.
- W2893065705 hasRelatedWork W2400534705 @default.
- W2893065705 hasRelatedWork W2418837291 @default.
- W2893065705 hasRelatedWork W2750722062 @default.
- W2893065705 hasRelatedWork W4281705786 @default.
- W2893065705 hasRelatedWork W74726072 @default.
- W2893065705 hasVolume "19" @default.
- W2893065705 isParatext "false" @default.
- W2893065705 isRetracted "false" @default.
- W2893065705 magId "2893065705" @default.
- W2893065705 workType "article" @default.