Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893113574> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2893113574 endingPage "e609" @default.
- W2893113574 startingPage "e608" @default.
- W2893113574 abstract "About 22 million people globally received antiretroviral therapy (ART) in 2017. 1 UNAIDSMiles to go. Closing gaps, breaking barriers, righting injustices. Joint United Nations Programme on HIV/AIDS, Geneva2018 Google Scholar In patients on ART, viral suppression is crucial for both the individual patient's clinical benefit and the community's HIV prevention benefit. A key reason for failure to achieve viral suppression is resistance to one or more drugs in the patient's antiretroviral regimen. Maintenance of a strict daily pill regimen can be challenging for patients; suboptimal adherence fosters drug resistance and the transmission of drug-resistant strains of HIV to others. Furthermore, resistance to non-nucleoside reverse transcriptase inhibitors (NNRTls) is widespread, emanating from previous use of nevirapine as a single drug regimen for prevention of mother-to child transmission. 2 Gupta RK Gregson J Parkin N et al. HIV-1 drug resistance before initiation or re-initiation of first-line antiretroviral therapy in low-income and middle-income countries: a systematic review and meta-regression analysis. Lancet Infect Dis. 2018; 18: 346-355 Summary Full Text Full Text PDF PubMed Scopus (228) Google Scholar Clinically relevant thresholds for ultrasensitive HIV drug resistance testing: a multi-country nested case-control studyUltrasensitive resistance testing for pretreatment drug resistance improved identification of people at risk of virological failure; however, this came with a reduction in our ability to identify people with viral suppression, especially at very low thresholds. Further modelling is needed to estimate the optimal trade-off for the 5% and 20% thresholds, balancing improved case finding against unnecessary regimen switching. Full-Text PDF" @default.
- W2893113574 created "2018-10-05" @default.
- W2893113574 creator A5082618220 @default.
- W2893113574 date "2018-11-01" @default.
- W2893113574 modified "2023-09-28" @default.
- W2893113574 title "Optimising the accuracy of HIV drug resistance assays" @default.
- W2893113574 cites W1840434126 @default.
- W2893113574 cites W2773554166 @default.
- W2893113574 cites W2893103482 @default.
- W2893113574 doi "https://doi.org/10.1016/s2352-3018(18)30211-x" @default.
- W2893113574 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30282604" @default.
- W2893113574 hasPublicationYear "2018" @default.
- W2893113574 type Work @default.
- W2893113574 sameAs 2893113574 @default.
- W2893113574 citedByCount "0" @default.
- W2893113574 crossrefType "journal-article" @default.
- W2893113574 hasAuthorship W2893113574A5082618220 @default.
- W2893113574 hasConcept C114851261 @default.
- W2893113574 hasConcept C119599485 @default.
- W2893113574 hasConcept C126322002 @default.
- W2893113574 hasConcept C127413603 @default.
- W2893113574 hasConcept C142462285 @default.
- W2893113574 hasConcept C159047783 @default.
- W2893113574 hasConcept C177713679 @default.
- W2893113574 hasConcept C2778451633 @default.
- W2893113574 hasConcept C2779130552 @default.
- W2893113574 hasConcept C2781413609 @default.
- W2893113574 hasConcept C2993143319 @default.
- W2893113574 hasConcept C3013748606 @default.
- W2893113574 hasConcept C54355233 @default.
- W2893113574 hasConcept C71924100 @default.
- W2893113574 hasConcept C761482 @default.
- W2893113574 hasConcept C86803240 @default.
- W2893113574 hasConceptScore W2893113574C114851261 @default.
- W2893113574 hasConceptScore W2893113574C119599485 @default.
- W2893113574 hasConceptScore W2893113574C126322002 @default.
- W2893113574 hasConceptScore W2893113574C127413603 @default.
- W2893113574 hasConceptScore W2893113574C142462285 @default.
- W2893113574 hasConceptScore W2893113574C159047783 @default.
- W2893113574 hasConceptScore W2893113574C177713679 @default.
- W2893113574 hasConceptScore W2893113574C2778451633 @default.
- W2893113574 hasConceptScore W2893113574C2779130552 @default.
- W2893113574 hasConceptScore W2893113574C2781413609 @default.
- W2893113574 hasConceptScore W2893113574C2993143319 @default.
- W2893113574 hasConceptScore W2893113574C3013748606 @default.
- W2893113574 hasConceptScore W2893113574C54355233 @default.
- W2893113574 hasConceptScore W2893113574C71924100 @default.
- W2893113574 hasConceptScore W2893113574C761482 @default.
- W2893113574 hasConceptScore W2893113574C86803240 @default.
- W2893113574 hasIssue "11" @default.
- W2893113574 hasLocation W28931135741 @default.
- W2893113574 hasLocation W28931135742 @default.
- W2893113574 hasOpenAccess W2893113574 @default.
- W2893113574 hasPrimaryLocation W28931135741 @default.
- W2893113574 hasRelatedWork W127451339 @default.
- W2893113574 hasRelatedWork W2109536957 @default.
- W2893113574 hasRelatedWork W2127943987 @default.
- W2893113574 hasRelatedWork W2344385793 @default.
- W2893113574 hasRelatedWork W2366933160 @default.
- W2893113574 hasRelatedWork W2395708473 @default.
- W2893113574 hasRelatedWork W2507485593 @default.
- W2893113574 hasRelatedWork W2756073838 @default.
- W2893113574 hasRelatedWork W3197334243 @default.
- W2893113574 hasRelatedWork W2515702025 @default.
- W2893113574 hasVolume "5" @default.
- W2893113574 isParatext "false" @default.
- W2893113574 isRetracted "false" @default.
- W2893113574 magId "2893113574" @default.
- W2893113574 workType "article" @default.