FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893123022> ?p ?o ?g. }

• W2893123022 endingPage "905" @default.
• W2893123022 startingPage "899" @default.
• W2893123022 abstract "Psoriatic arthritis (PsA) is a chronic inflammatory disease characterized by the presence of psoriasis, arthritis, and enthesitis, with the association of other musculoskeletal and extra-articular manifestations. Current treatment of PsA is based on the use of conventional, biological and targeted synthetic disease modifying anti-rheumatic drugs; however, patients may not respond or have a loss of response to these agents. Recently, a deeper understanding of the pathogenetic mechanisms has made possible the development of new drugs that actively interact with the activation of immune system, inhibiting the co-stimulation between antigen-presenting cells and lymphocytes. Areas covered: The aim of this paper is to review the role of the activation of the immune system in the pathogenesis and treatment of PsA, with a discussion on the emerging CTLA4Ig drugs (abatacept) for PsA. A search in PubMed and EMBASE was performed with the keywords: 'abatacept', 'CTLA4,' and 'Psoriatic Arthritis.' We considered preclinical studies, phase I, II and III clinical trials. Expert commentary: The inhibitors of co-stimulation may represent an effective treatment strategy by acting on the very early phase of the immunological process that brought about the development of inflammation and activation of the immune system, mainly for patients with peripheral joint involvement and mild psoriasis." @default.
• W2893123022 created "2018-10-05" @default.
• W2893123022 creator A5012801105 @default.
• W2893123022 creator A5015866836 @default.
• W2893123022 creator A5088736161 @default.
• W2893123022 date "2018-10-12" @default.
• W2893123022 modified "2023-10-16" @default.
• W2893123022 title "Abatacept for the treatment of psoriatic arthritis" @default.
• W2893123022 cites W1898625467 @default.
• W2893123022 cites W1967046459 @default.
• W2893123022 cites W1973040111 @default.
• W2893123022 cites W2009392302 @default.
• W2893123022 cites W2021708616 @default.
• W2893123022 cites W2048020246 @default.
• W2893123022 cites W2049217242 @default.
• W2893123022 cites W2062453785 @default.
• W2893123022 cites W2063861785 @default.
• W2893123022 cites W2079974518 @default.
• W2893123022 cites W2091783976 @default.
• W2893123022 cites W2103524303 @default.
• W2893123022 cites W2108984264 @default.
• W2893123022 cites W2120096107 @default.
• W2893123022 cites W2125956827 @default.
• W2893123022 cites W2128119287 @default.
• W2893123022 cites W2131136878 @default.
• W2893123022 cites W2137096190 @default.
• W2893123022 cites W2146603828 @default.
• W2893123022 cites W2149118348 @default.
• W2893123022 cites W2200305809 @default.
• W2893123022 cites W2290423455 @default.
• W2893123022 cites W2294293075 @default.
• W2893123022 cites W2299210279 @default.
• W2893123022 cites W2395845086 @default.
• W2893123022 cites W2553042376 @default.
• W2893123022 cites W2562753848 @default.
• W2893123022 cites W2611521096 @default.
• W2893123022 cites W2729444380 @default.
• W2893123022 cites W2753594593 @default.
• W2893123022 cites W2766717228 @default.
• W2893123022 cites W2783502763 @default.
• W2893123022 cites W2788248051 @default.
• W2893123022 cites W2797783564 @default.
• W2893123022 cites W2802952762 @default.
• W2893123022 doi "https://doi.org/10.1080/1744666x.2018.1527218" @default.
• W2893123022 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30246575" @default.
• W2893123022 hasPublicationYear "2018" @default.
• W2893123022 type Work @default.
• W2893123022 sameAs 2893123022 @default.
• W2893123022 citedByCount "7" @default.
• W2893123022 countsByYear W28931230222019 @default.
• W2893123022 countsByYear W28931230222020 @default.
• W2893123022 countsByYear W28931230222021 @default.
• W2893123022 countsByYear W28931230222023 @default.
• W2893123022 crossrefType "journal-article" @default.
• W2893123022 hasAuthorship W2893123022A5012801105 @default.
• W2893123022 hasAuthorship W2893123022A5015866836 @default.
• W2893123022 hasAuthorship W2893123022A5088736161 @default.
• W2893123022 hasConcept C159654299 @default.
• W2893123022 hasConcept C203014093 @default.
• W2893123022 hasConcept C2776260265 @default.
• W2893123022 hasConcept C2777077863 @default.
• W2893123022 hasConcept C2777575956 @default.
• W2893123022 hasConcept C2779605438 @default.
• W2893123022 hasConcept C2780131103 @default.
• W2893123022 hasConcept C2780564577 @default.
• W2893123022 hasConcept C2780653079 @default.
• W2893123022 hasConcept C71924100 @default.
• W2893123022 hasConcept C8891405 @default.
• W2893123022 hasConceptScore W2893123022C159654299 @default.
• W2893123022 hasConceptScore W2893123022C203014093 @default.
• W2893123022 hasConceptScore W2893123022C2776260265 @default.
• W2893123022 hasConceptScore W2893123022C2777077863 @default.
• W2893123022 hasConceptScore W2893123022C2777575956 @default.
• W2893123022 hasConceptScore W2893123022C2779605438 @default.
• W2893123022 hasConceptScore W2893123022C2780131103 @default.
• W2893123022 hasConceptScore W2893123022C2780564577 @default.
• W2893123022 hasConceptScore W2893123022C2780653079 @default.
• W2893123022 hasConceptScore W2893123022C71924100 @default.
• W2893123022 hasConceptScore W2893123022C8891405 @default.
• W2893123022 hasIssue "11" @default.
• W2893123022 hasLocation W28931230221 @default.
• W2893123022 hasLocation W28931230222 @default.
• W2893123022 hasOpenAccess W2893123022 @default.
• W2893123022 hasPrimaryLocation W28931230221 @default.
• W2893123022 hasRelatedWork W1566732118 @default.
• W2893123022 hasRelatedWork W1990932859 @default.
• W2893123022 hasRelatedWork W2071065611 @default.
• W2893123022 hasRelatedWork W2141972836 @default.
• W2893123022 hasRelatedWork W2469713984 @default.
• W2893123022 hasRelatedWork W2518783584 @default.
• W2893123022 hasRelatedWork W3188503192 @default.
• W2893123022 hasRelatedWork W4229733615 @default.
• W2893123022 hasRelatedWork W4284968964 @default.
• W2893123022 hasRelatedWork W4362505916 @default.
• W2893123022 hasVolume "14" @default.
• W2893123022 isParatext "false" @default.
• W2893123022 isRetracted "false" @default.
• W2893123022 magId "2893123022" @default.

• next