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• W2893136373 abstract "Abstract The mesial prefrontal cortex, cingulate cortex and the ventral striatum are key nodes of the human mesial fronto-striatal circuit involved in decision-making and executive function and pathological disorders. Here we ask whether deep wide-field repetitive transcranial magnetic stimulation (rTMS) targeting the mesial prefrontal cortex (MPFC) influences resting state functional connectivity. In Study 1, we examined functional connectivity using resting state multi-echo and independent components analysis in 154 healthy subjects to characterize default connectivity in the MPFC and mid-cingulate cortex (MCC). In Study 2, we used inhibitory, 1 Hz deep rTMS with the H7-coil targeting MPFC and dorsal anterior cingulate (dACC) in a separate group of 20 healthy volunteers and examined pre-and post-TMS functional connectivity using seed-based and independent components analysis. In Study 1, we show that MPFC and MCC have distinct patterns of functional connectivity with MPFC–ventral striatum showing negative, whereas MCC–ventral striatum showing positive functional connectivity. Low-frequency rTMS decreased functional connectivity of MPFC and dACC with the ventral striatum. We further showed enhanced connectivity between MCC and ventral striatum. These findings emphasize how deep inhibitory rTMS using the H7-coil can influence underlying network functional connectivity by decreasing connectivity of the targeted MPFC regions, thus potentially enhancing response inhibition and decreasing drug cue reactivity processes relevant to addictions. The unexpected finding of enhanced default connectivity between MCC and ventral striatum may be related to the decreased influence and connectivity between the MPFC and MCC. These findings are highly relevant to the treatment of disorders relying on the mesioprefrontal–cingulo–striatal circuit." @default.
• W2893136373 created "2018-10-05" @default.
• W2893136373 creator A5005566965 @default.
• W2893136373 creator A5010002316 @default.
• W2893136373 creator A5035810128 @default.
• W2893136373 creator A5046757283 @default.
• W2893136373 creator A5057394764 @default.
• W2893136373 creator A5063825764 @default.
• W2893136373 creator A5074074054 @default.
• W2893136373 creator A5080322312 @default.
• W2893136373 creator A5090133744 @default.
• W2893136373 creator A5091650785 @default.
• W2893136373 date "2018-10-01" @default.
• W2893136373 modified "2023-09-27" @default.
• W2893136373 title "Modulation of Resting Connectivity Between the Mesial Frontal Cortex and Basal Ganglia" @default.
• W2893136373 cites W1462915242 @default.
• W2893136373 cites W1513715143 @default.
• W2893136373 cites W1556447985 @default.
• W2893136373 cites W1593548233 @default.
• W2893136373 cites W1869019363 @default.
• W2893136373 cites W1928928322 @default.
• W2893136373 cites W1964194422 @default.
• W2893136373 cites W1965061301 @default.
• W2893136373 cites W1966460949 @default.
• W2893136373 cites W1968016381 @default.
• W2893136373 cites W1969873014 @default.
• W2893136373 cites W1970452940 @default.
• W2893136373 cites W1973596946 @default.
• W2893136373 cites W1978713359 @default.
• W2893136373 cites W1983183519 @default.
• W2893136373 cites W1986350274 @default.
• W2893136373 cites W1988751658 @default.
• W2893136373 cites W1989474930 @default.
• W2893136373 cites W1990701757 @default.
• W2893136373 cites W1991165133 @default.
• W2893136373 cites W2008098183 @default.
• W2893136373 cites W2008492231 @default.
• W2893136373 cites W2009326946 @default.
• W2893136373 cites W2009341243 @default.
• W2893136373 cites W2009494091 @default.
• W2893136373 cites W2012440798 @default.
• W2893136373 cites W2012635324 @default.
• W2893136373 cites W2020327987 @default.
• W2893136373 cites W2024289002 @default.
• W2893136373 cites W2024832506 @default.
• W2893136373 cites W2027781650 @default.
• W2893136373 cites W2030055333 @default.
• W2893136373 cites W2030902100 @default.
• W2893136373 cites W2031572915 @default.
• W2893136373 cites W2031821572 @default.
• W2893136373 cites W2034753893 @default.
• W2893136373 cites W2035678379 @default.
• W2893136373 cites W2035818685 @default.
• W2893136373 cites W2036037381 @default.
• W2893136373 cites W2038304716 @default.
• W2893136373 cites W2041127567 @default.
• W2893136373 cites W2046713808 @default.
• W2893136373 cites W2052345579 @default.
• W2893136373 cites W2052445433 @default.
• W2893136373 cites W2056417054 @default.
• W2893136373 cites W2056465968 @default.
• W2893136373 cites W2058467798 @default.
• W2893136373 cites W2058488977 @default.
• W2893136373 cites W2059354256 @default.
• W2893136373 cites W2059606609 @default.
• W2893136373 cites W2060870333 @default.
• W2893136373 cites W2061551969 @default.
• W2893136373 cites W2061965334 @default.
• W2893136373 cites W2062103870 @default.
• W2893136373 cites W2062477851 @default.
• W2893136373 cites W2065187390 @default.
• W2893136373 cites W2066584179 @default.
• W2893136373 cites W2068782491 @default.
• W2893136373 cites W2072959524 @default.
• W2893136373 cites W2074955389 @default.
• W2893136373 cites W2075094758 @default.
• W2893136373 cites W2075547697 @default.
• W2893136373 cites W2078530990 @default.
• W2893136373 cites W2078858378 @default.
• W2893136373 cites W2079355604 @default.
• W2893136373 cites W2079450984 @default.
• W2893136373 cites W2081169891 @default.
• W2893136373 cites W2082014247 @default.
• W2893136373 cites W2082526227 @default.
• W2893136373 cites W2088098333 @default.
• W2893136373 cites W2088099997 @default.
• W2893136373 cites W2105220251 @default.
• W2893136373 cites W2105337517 @default.
• W2893136373 cites W2105653311 @default.
• W2893136373 cites W2106674256 @default.
• W2893136373 cites W2107360535 @default.
• W2893136373 cites W2116268668 @default.
• W2893136373 cites W2116658855 @default.
• W2893136373 cites W2117621792 @default.
• W2893136373 cites W2117726420 @default.
• W2893136373 cites W2118536546 @default.
• W2893136373 cites W2118761232 @default.
• W2893136373 cites W2119102767 @default.
• W2893136373 cites W2121252865 @default.
• W2893136373 cites W2123712730 @default.

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