Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893144735> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W2893144735 endingPage "56" @default.
- W2893144735 startingPage "56" @default.
- W2893144735 abstract "BACKGROUND: This study attempts to highlight the vasodilatation effects of L-carnitine on the left internal mammary artery (LIMA) in patients undergoing coronary artery bypass graft (CABG) surgery.PATIENTS AND METHODS: A total of 45 male patients (age 55–60 years), and body weight (70–75 kg) were included in this study. Participants were planned to undertake elective CABG surgery, and they were randomly allocated into two study groups as follows: Control group included 15 patients received placebo capsule (lactose capsules), twice daily for 3 successive days before CABG surgery. L-carnitine-treated group included the remaining 30 participants received L-carnitine capsules, 500 mg twice daily for 3 days before CABG surgery.RESULTS: The two groups were comparable according to their age and comorbidities. There was significant increase in the plasma levels of endothelial nitric oxide synthase (eNOS) and matrix Gla-protein (MGP) among the L-carnitine group as compared with the control group (P < 0.001, P = 0.011, respectively). At the same time, tissue eNOS levels and tissue MGP levels were significantly higher (P = 0.078, P < 0.001, respectively) in the L-carnitine group as compared with the control group. Plasma levels of angiotensin II (ANGII) and endothelin-1 (ET-1) levels were significantly lower (P < 0.001) in the L-carnitine group. Tissue levels of ANGII and ET-1 were significantly lower (P = 0.039, P < 0.001, respectively).CONCLUSIONS: We can conclude that L-carnitine has potent vasodilatation effects on LIMA during CABG surgery as evidenced by the increase in plasma and tissue levels of eNOS and MGP, associated with a decrease in plasma and tissue levels of ANGII and ET-1." @default.
- W2893144735 created "2018-10-05" @default.
- W2893144735 creator A5031179495 @default.
- W2893144735 creator A5060055342 @default.
- W2893144735 creator A5073823011 @default.
- W2893144735 creator A5075617942 @default.
- W2893144735 creator A5078748374 @default.
- W2893144735 creator A5087609544 @default.
- W2893144735 date "2018-01-01" @default.
- W2893144735 modified "2023-10-16" @default.
- W2893144735 title "Response of internal mammary artery wall to L-carnitine in patients undergoing coronary artery bypass" @default.
- W2893144735 doi "https://doi.org/10.4103/vit.vit_11_18" @default.
- W2893144735 hasPublicationYear "2018" @default.
- W2893144735 type Work @default.
- W2893144735 sameAs 2893144735 @default.
- W2893144735 citedByCount "1" @default.
- W2893144735 countsByYear W28931447352021 @default.
- W2893144735 crossrefType "journal-article" @default.
- W2893144735 hasAuthorship W2893144735A5031179495 @default.
- W2893144735 hasAuthorship W2893144735A5060055342 @default.
- W2893144735 hasAuthorship W2893144735A5073823011 @default.
- W2893144735 hasAuthorship W2893144735A5075617942 @default.
- W2893144735 hasAuthorship W2893144735A5078748374 @default.
- W2893144735 hasAuthorship W2893144735A5087609544 @default.
- W2893144735 hasBestOaLocation W28931447351 @default.
- W2893144735 hasConcept C126322002 @default.
- W2893144735 hasConcept C134018914 @default.
- W2893144735 hasConcept C164705383 @default.
- W2893144735 hasConcept C2776820930 @default.
- W2893144735 hasConcept C2777622882 @default.
- W2893144735 hasConcept C2778213512 @default.
- W2893144735 hasConcept C2778326061 @default.
- W2893144735 hasConcept C2778435403 @default.
- W2893144735 hasConcept C519581460 @default.
- W2893144735 hasConcept C71924100 @default.
- W2893144735 hasConceptScore W2893144735C126322002 @default.
- W2893144735 hasConceptScore W2893144735C134018914 @default.
- W2893144735 hasConceptScore W2893144735C164705383 @default.
- W2893144735 hasConceptScore W2893144735C2776820930 @default.
- W2893144735 hasConceptScore W2893144735C2777622882 @default.
- W2893144735 hasConceptScore W2893144735C2778213512 @default.
- W2893144735 hasConceptScore W2893144735C2778326061 @default.
- W2893144735 hasConceptScore W2893144735C2778435403 @default.
- W2893144735 hasConceptScore W2893144735C519581460 @default.
- W2893144735 hasConceptScore W2893144735C71924100 @default.
- W2893144735 hasIssue "2" @default.
- W2893144735 hasLocation W28931447351 @default.
- W2893144735 hasOpenAccess W2893144735 @default.
- W2893144735 hasPrimaryLocation W28931447351 @default.
- W2893144735 hasRelatedWork W1512776992 @default.
- W2893144735 hasRelatedWork W1975536848 @default.
- W2893144735 hasRelatedWork W2099366831 @default.
- W2893144735 hasRelatedWork W2114204950 @default.
- W2893144735 hasRelatedWork W2145618820 @default.
- W2893144735 hasRelatedWork W2146211406 @default.
- W2893144735 hasRelatedWork W2148878791 @default.
- W2893144735 hasRelatedWork W2163591087 @default.
- W2893144735 hasRelatedWork W2358606101 @default.
- W2893144735 hasRelatedWork W3143717565 @default.
- W2893144735 hasVolume "1" @default.
- W2893144735 isParatext "false" @default.
- W2893144735 isRetracted "false" @default.
- W2893144735 magId "2893144735" @default.
- W2893144735 workType "article" @default.