Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893157614> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2893157614 endingPage "42" @default.
- W2893157614 startingPage "42" @default.
- W2893157614 abstract "Bacterial resistance towards the existing class of antibacterial drugs continues to increase, posing a significant threat to the clinical usefulness of these drugs. These increasing and alarming rates of antibacterial resistance development and the decline in the number of new antibacterial drugs’ approval continue to serve as a major impetus for research into the discovery and development of new antibacterial agents. We synthesized a series of d-/l-alaninyl substituted triazolyl oxazolidinone derivatives and evaluated their antibacterial activity against selected standard Gram-positive and Gram-negative bacterial strains. Overall, the compounds showed moderate to strong antibacterial activity. Compounds 9d and 10d (d- and l-alaninyl derivatives bearing the 3,5-dinitrobenzoyl substituent), 10e (l-alaninyl derivative bearing the 5-nitrofurancarbonyl group) and 9f and 10f (d- and l-alaninyl derivatives bearing the 5-nitrothiophene carbonyl moiety) demonstrated antibacterial activity (MIC: 2 µg/mL) against Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis and Moraxella catarrhalis standard bacterial strains. No significant differences were noticeable between the antibacterial activity of the d- and l-alaninyl derivatives as a result of the stereochemistry of the compounds." @default.
- W2893157614 created "2018-10-05" @default.
- W2893157614 creator A5047090021 @default.
- W2893157614 creator A5072543163 @default.
- W2893157614 creator A5087549701 @default.
- W2893157614 date "2018-09-26" @default.
- W2893157614 modified "2023-09-25" @default.
- W2893157614 title "Structure-Antibacterial Activity Relationships of N-Substituted-(d-/l-Alaninyl) 1H-1,2,3-Triazolylmethyl Oxazolidinones" @default.
- W2893157614 cites W1529101966 @default.
- W2893157614 cites W1947810765 @default.
- W2893157614 cites W1965602820 @default.
- W2893157614 cites W1969960330 @default.
- W2893157614 cites W1987879445 @default.
- W2893157614 cites W1990214137 @default.
- W2893157614 cites W1998839868 @default.
- W2893157614 cites W2010294057 @default.
- W2893157614 cites W2012206896 @default.
- W2893157614 cites W2013004250 @default.
- W2893157614 cites W2017662055 @default.
- W2893157614 cites W2044485940 @default.
- W2893157614 cites W2044768462 @default.
- W2893157614 cites W2045301368 @default.
- W2893157614 cites W2055547621 @default.
- W2893157614 cites W2068051461 @default.
- W2893157614 cites W2071342482 @default.
- W2893157614 cites W2075594360 @default.
- W2893157614 cites W2090816462 @default.
- W2893157614 cites W2108934165 @default.
- W2893157614 cites W2150324756 @default.
- W2893157614 cites W2168635615 @default.
- W2893157614 cites W2180406838 @default.
- W2893157614 cites W2318565918 @default.
- W2893157614 cites W2463990453 @default.
- W2893157614 cites W2524062943 @default.
- W2893157614 cites W2757978500 @default.
- W2893157614 cites W2972446051 @default.
- W2893157614 doi "https://doi.org/10.3390/scipharm86040042" @default.
- W2893157614 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30261667" @default.
- W2893157614 hasPublicationYear "2018" @default.
- W2893157614 type Work @default.
- W2893157614 sameAs 2893157614 @default.
- W2893157614 citedByCount "1" @default.
- W2893157614 countsByYear W28931576142023 @default.
- W2893157614 crossrefType "journal-article" @default.
- W2893157614 hasAuthorship W2893157614A5047090021 @default.
- W2893157614 hasAuthorship W2893157614A5072543163 @default.
- W2893157614 hasAuthorship W2893157614A5087549701 @default.
- W2893157614 hasBestOaLocation W28931576141 @default.
- W2893157614 hasConcept C185592680 @default.
- W2893157614 hasConcept C2776551000 @default.
- W2893157614 hasConcept C2777949923 @default.
- W2893157614 hasConcept C2778689049 @default.
- W2893157614 hasConcept C2779489039 @default.
- W2893157614 hasConcept C2779895986 @default.
- W2893157614 hasConcept C2780104969 @default.
- W2893157614 hasConcept C523546767 @default.
- W2893157614 hasConcept C54355233 @default.
- W2893157614 hasConcept C71240020 @default.
- W2893157614 hasConcept C86803240 @default.
- W2893157614 hasConcept C89423630 @default.
- W2893157614 hasConceptScore W2893157614C185592680 @default.
- W2893157614 hasConceptScore W2893157614C2776551000 @default.
- W2893157614 hasConceptScore W2893157614C2777949923 @default.
- W2893157614 hasConceptScore W2893157614C2778689049 @default.
- W2893157614 hasConceptScore W2893157614C2779489039 @default.
- W2893157614 hasConceptScore W2893157614C2779895986 @default.
- W2893157614 hasConceptScore W2893157614C2780104969 @default.
- W2893157614 hasConceptScore W2893157614C523546767 @default.
- W2893157614 hasConceptScore W2893157614C54355233 @default.
- W2893157614 hasConceptScore W2893157614C71240020 @default.
- W2893157614 hasConceptScore W2893157614C86803240 @default.
- W2893157614 hasConceptScore W2893157614C89423630 @default.
- W2893157614 hasIssue "4" @default.
- W2893157614 hasLocation W28931576141 @default.
- W2893157614 hasLocation W28931576142 @default.
- W2893157614 hasLocation W28931576143 @default.
- W2893157614 hasLocation W28931576144 @default.
- W2893157614 hasOpenAccess W2893157614 @default.
- W2893157614 hasPrimaryLocation W28931576141 @default.
- W2893157614 hasRelatedWork W2008512511 @default.
- W2893157614 hasRelatedWork W2086421136 @default.
- W2893157614 hasRelatedWork W2091983121 @default.
- W2893157614 hasRelatedWork W2115214687 @default.
- W2893157614 hasRelatedWork W2326830576 @default.
- W2893157614 hasRelatedWork W2409890776 @default.
- W2893157614 hasRelatedWork W2768680059 @default.
- W2893157614 hasRelatedWork W2795968446 @default.
- W2893157614 hasRelatedWork W2893157614 @default.
- W2893157614 hasRelatedWork W2996891616 @default.
- W2893157614 hasVolume "86" @default.
- W2893157614 isParatext "false" @default.
- W2893157614 isRetracted "false" @default.
- W2893157614 magId "2893157614" @default.
- W2893157614 workType "article" @default.