FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893163961> ?p ?o ?g. }

• W2893163961 endingPage "199" @default.
• W2893163961 startingPage "193" @default.
• W2893163961 abstract "Hepatitis C virus (HCV) infection often leads to chronic hepatitis that can progress to liver cirrhosis and hepatocellular carcinoma (HCC). Although HCV infection is expected to decrease due to the high rate of HCV eradication via the rapid dissemination and use of directly acting antivirals, HCV infection remains a leading cause of HCC. Although the mechanisms underlying the HCC development are not fully understood, oxidative stress is present to a greater degree in HCV infection than in other inflammatory liver diseases and has been proposed as a major mechanism of liver injury in patients with chronic hepatitis C. Hepatocellular mitochondrial alterations and iron accumulation are well-known characteristics in patients with chronic hepatitis C and are closely related to oxidative stress, since the mitochondria are the main site of reactive oxygen species generation, and iron produces hydroxy radicals via the Fenton reaction. In addition, phlebotomy is an iron reduction approach that aims to lower serum transaminase levels in patients with chronic hepatitis C. Here, we review and discuss the mechanisms by which HCV induces mitochondrial damage and iron accumulation in the liver and offer new insights concerning how mitochondrial damage and iron accumulation are linked to the development of HCC." @default.
• W2893163961 created "2018-10-05" @default.
• W2893163961 creator A5009254097 @default.
• W2893163961 creator A5025371497 @default.
• W2893163961 creator A5051600189 @default.
• W2893163961 creator A5089944591 @default.
• W2893163961 date "2019-03-01" @default.
• W2893163961 modified "2023-10-12" @default.
• W2893163961 title "Mitochondrial damage and iron metabolic dysregulation in hepatitis C virus infection" @default.
• W2893163961 cites W1495909545 @default.
• W2893163961 cites W1574880093 @default.
• W2893163961 cites W1575882906 @default.
• W2893163961 cites W1590045749 @default.
• W2893163961 cites W1761222131 @default.
• W2893163961 cites W1838530486 @default.
• W2893163961 cites W1964185091 @default.
• W2893163961 cites W1967964480 @default.
• W2893163961 cites W1968603331 @default.
• W2893163961 cites W1970739518 @default.
• W2893163961 cites W1972590376 @default.
• W2893163961 cites W1976887467 @default.
• W2893163961 cites W1980737728 @default.
• W2893163961 cites W1984590625 @default.
• W2893163961 cites W1988150327 @default.
• W2893163961 cites W1988870963 @default.
• W2893163961 cites W1989061093 @default.
• W2893163961 cites W1993747338 @default.
• W2893163961 cites W2003682019 @default.
• W2893163961 cites W2004283265 @default.
• W2893163961 cites W2004704734 @default.
• W2893163961 cites W2005077809 @default.
• W2893163961 cites W2005258127 @default.
• W2893163961 cites W2011616562 @default.
• W2893163961 cites W2013092102 @default.
• W2893163961 cites W2024985676 @default.
• W2893163961 cites W2025063713 @default.
• W2893163961 cites W2026543492 @default.
• W2893163961 cites W2026954536 @default.
• W2893163961 cites W2031729422 @default.
• W2893163961 cites W2038976751 @default.
• W2893163961 cites W2039007136 @default.
• W2893163961 cites W2046878952 @default.
• W2893163961 cites W2048689142 @default.
• W2893163961 cites W2049912996 @default.
• W2893163961 cites W2050430849 @default.
• W2893163961 cites W2050833520 @default.
• W2893163961 cites W2052151802 @default.
• W2893163961 cites W2053009244 @default.
• W2893163961 cites W2053978445 @default.
• W2893163961 cites W2054193843 @default.
• W2893163961 cites W2059246129 @default.
• W2893163961 cites W2061122330 @default.
• W2893163961 cites W2062216905 @default.
• W2893163961 cites W2063072742 @default.
• W2893163961 cites W2065527667 @default.
• W2893163961 cites W2065585203 @default.
• W2893163961 cites W2068700852 @default.
• W2893163961 cites W2069139764 @default.
• W2893163961 cites W2069466682 @default.
• W2893163961 cites W2074114272 @default.
• W2893163961 cites W2076709487 @default.
• W2893163961 cites W2078132151 @default.
• W2893163961 cites W2081147927 @default.
• W2893163961 cites W2082886212 @default.
• W2893163961 cites W2082933842 @default.
• W2893163961 cites W2094748234 @default.
• W2893163961 cites W2095301528 @default.
• W2893163961 cites W2097246425 @default.
• W2893163961 cites W2101162595 @default.
• W2893163961 cites W2101348459 @default.
• W2893163961 cites W2103067865 @default.
• W2893163961 cites W2104241630 @default.
• W2893163961 cites W2110728364 @default.
• W2893163961 cites W2119371081 @default.
• W2893163961 cites W2127481048 @default.
• W2893163961 cites W2131007152 @default.
• W2893163961 cites W2138718559 @default.
• W2893163961 cites W2139439041 @default.
• W2893163961 cites W2144687501 @default.
• W2893163961 cites W2145783052 @default.
• W2893163961 cites W2146743869 @default.
• W2893163961 cites W2155015733 @default.
• W2893163961 cites W2161535669 @default.
• W2893163961 cites W2161998284 @default.
• W2893163961 cites W2163469200 @default.
• W2893163961 cites W2164481110 @default.
• W2893163961 cites W2170760996 @default.
• W2893163961 cites W2172197126 @default.
• W2893163961 cites W2288541894 @default.
• W2893163961 cites W2480725775 @default.
• W2893163961 cites W2552432336 @default.
• W2893163961 cites W2555711826 @default.
• W2893163961 cites W2772781313 @default.
• W2893163961 cites W2884486379 @default.
• W2893163961 cites W8890124 @default.
• W2893163961 doi "https://doi.org/10.1016/j.freeradbiomed.2018.09.044" @default.
• W2893163961 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30268888" @default.
• W2893163961 hasPublicationYear "2019" @default.

• next