Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893201416> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2893201416 endingPage "961" @default.
- W2893201416 startingPage "954" @default.
- W2893201416 abstract "Objectives: Evaluate the safety and clinical response of complementary treatment with European mistletoe extracts during chemotherapy. Design: Monocentric controlled trial with 95 patients randomized into three groups. Settings/Location: National Cancer Research Center of Serbia. Subjects: Breast cancer patients (stage T1–3N0–2M0) undergoing surgery and adjuvant chemotherapy with six cycles of cyclophosphamide, adriamycin, and 5-fluorouracil. Interventions: Two different European mistletoe extracts (Helixor A, Iscador M Spez) were injected three times per week during 18 weeks of chemotherapy in the mistletoe group. Five-year follow-up of routine visits was documented in case report forms. Outcome measures: Safety was assessed by measuring adverse events, body temperature during chemotherapy, and probability of relapse or metastasis in a 5-year follow-up. During chemotherapy, the neutrophil count and quality of life according to EORTC QLQ-C30 were assessed. Results: The two patient groups receiving different complementary mistletoe treatments were integrated into one mistletoe group for this safety analysis. Patients in the mistletoe group did not develop more fever symptoms than patients in the control group (two short-term events in each group). No significant differences in probability of relapse or metastasis were measured between the groups (p = 0.7637). The mistletoe group showed a trend toward less neutropenia (p = 0.178) and improved pain and appetite loss scores (p < 0.0001 and p = 0.047, respectively) while having positive, but not significant, impact on other EORTC QLQ-C30 scores. Conclusions: Mistletoe extracts were safe in this clinical study. Neither did subcutaneous injections induce fever, nor did they influence the frequency of relapse and metastasis within 5 years. This result suggests that mistletoe extracts had no adverse interactions with the anticancer agents used in this study. Furthermore, certain side effects of chemotherapy decreased under this complementary treatment in breast cancer patients." @default.
- W2893201416 created "2018-10-05" @default.
- W2893201416 creator A5066702896 @default.
- W2893201416 creator A5077599009 @default.
- W2893201416 date "2018-09-01" @default.
- W2893201416 modified "2023-10-01" @default.
- W2893201416 title "Complementary Treatment with Mistletoe Extracts During Chemotherapy: Safety, Neutropenia, Fever, and Quality of Life Assessed in a Randomized Study" @default.
- W2893201416 cites W1971082430 @default.
- W2893201416 cites W1995209781 @default.
- W2893201416 cites W2017476000 @default.
- W2893201416 cites W2020874343 @default.
- W2893201416 cites W2040277279 @default.
- W2893201416 cites W2045224875 @default.
- W2893201416 cites W2048711771 @default.
- W2893201416 cites W2060275693 @default.
- W2893201416 cites W2064000838 @default.
- W2893201416 cites W2102958754 @default.
- W2893201416 cites W2110737147 @default.
- W2893201416 cites W2113920410 @default.
- W2893201416 cites W2130529614 @default.
- W2893201416 cites W2134690055 @default.
- W2893201416 cites W2164389477 @default.
- W2893201416 cites W2167571044 @default.
- W2893201416 cites W2178767900 @default.
- W2893201416 cites W2315409619 @default.
- W2893201416 cites W2336570215 @default.
- W2893201416 cites W2506768159 @default.
- W2893201416 cites W2530348352 @default.
- W2893201416 cites W68891328 @default.
- W2893201416 doi "https://doi.org/10.1089/acm.2018.0159" @default.
- W2893201416 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6157372" @default.
- W2893201416 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30247950" @default.
- W2893201416 hasPublicationYear "2018" @default.
- W2893201416 type Work @default.
- W2893201416 sameAs 2893201416 @default.
- W2893201416 citedByCount "23" @default.
- W2893201416 countsByYear W28932014162018 @default.
- W2893201416 countsByYear W28932014162019 @default.
- W2893201416 countsByYear W28932014162020 @default.
- W2893201416 countsByYear W28932014162021 @default.
- W2893201416 countsByYear W28932014162022 @default.
- W2893201416 countsByYear W28932014162023 @default.
- W2893201416 crossrefType "journal-article" @default.
- W2893201416 hasAuthorship W2893201416A5066702896 @default.
- W2893201416 hasAuthorship W2893201416A5077599009 @default.
- W2893201416 hasBestOaLocation W28932014161 @default.
- W2893201416 hasConcept C121608353 @default.
- W2893201416 hasConcept C126322002 @default.
- W2893201416 hasConcept C141071460 @default.
- W2893201416 hasConcept C143998085 @default.
- W2893201416 hasConcept C159110408 @default.
- W2893201416 hasConcept C168563851 @default.
- W2893201416 hasConcept C197934379 @default.
- W2893201416 hasConcept C2776694085 @default.
- W2893201416 hasConcept C2776755627 @default.
- W2893201416 hasConcept C2777063308 @default.
- W2893201416 hasConcept C2777863537 @default.
- W2893201416 hasConcept C2779951463 @default.
- W2893201416 hasConcept C535046627 @default.
- W2893201416 hasConcept C71924100 @default.
- W2893201416 hasConceptScore W2893201416C121608353 @default.
- W2893201416 hasConceptScore W2893201416C126322002 @default.
- W2893201416 hasConceptScore W2893201416C141071460 @default.
- W2893201416 hasConceptScore W2893201416C143998085 @default.
- W2893201416 hasConceptScore W2893201416C159110408 @default.
- W2893201416 hasConceptScore W2893201416C168563851 @default.
- W2893201416 hasConceptScore W2893201416C197934379 @default.
- W2893201416 hasConceptScore W2893201416C2776694085 @default.
- W2893201416 hasConceptScore W2893201416C2776755627 @default.
- W2893201416 hasConceptScore W2893201416C2777063308 @default.
- W2893201416 hasConceptScore W2893201416C2777863537 @default.
- W2893201416 hasConceptScore W2893201416C2779951463 @default.
- W2893201416 hasConceptScore W2893201416C535046627 @default.
- W2893201416 hasConceptScore W2893201416C71924100 @default.
- W2893201416 hasIssue "9-10" @default.
- W2893201416 hasLocation W28932014161 @default.
- W2893201416 hasLocation W28932014162 @default.
- W2893201416 hasLocation W28932014163 @default.
- W2893201416 hasLocation W28932014164 @default.
- W2893201416 hasOpenAccess W2893201416 @default.
- W2893201416 hasPrimaryLocation W28932014161 @default.
- W2893201416 hasRelatedWork W118279503 @default.
- W2893201416 hasRelatedWork W2047427543 @default.
- W2893201416 hasRelatedWork W2047967234 @default.
- W2893201416 hasRelatedWork W2051287676 @default.
- W2893201416 hasRelatedWork W2068796910 @default.
- W2893201416 hasRelatedWork W2091205535 @default.
- W2893201416 hasRelatedWork W2437448088 @default.
- W2893201416 hasRelatedWork W4248700200 @default.
- W2893201416 hasRelatedWork W4285048480 @default.
- W2893201416 hasRelatedWork W2427250343 @default.
- W2893201416 hasVolume "24" @default.
- W2893201416 isParatext "false" @default.
- W2893201416 isRetracted "false" @default.
- W2893201416 magId "2893201416" @default.
- W2893201416 workType "article" @default.