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- W2893218327 abstract "Introduction In 2015, approximately 42,400 women died as a result of hypertensive disorders worldwide, over 99% of which occured in low and middle-income countries (LMIC). The majority of prevalence data is based on small observational studies or modelled data. Objective To describe the prevalence of eclampsia in LMIC. Methods This is a secondary analysis of stepped-wedge randomised controlled trial undertaken in ten clusters across Africa, India and Haiti between April 2016 and November 2017. Cluster level consent was obtained therefore all women presenting for maternity care were eligible. Eclampsia data was prospectively collected from routine data sources and active case finding. Results A total of 2692 women experienced eclampsia and there were 536,233 deliveries across 287 facilities. Prevalence of eclampsia was 0.5% but varied between sites (Table 1). 45% of women experienced their first fit in the community, with 24% occurring in clinic and 31% in hospital. Magnesium availability differed between clusters (Table 1) but availability within clusters did not significantly fluctuate over time (rate of change 0.2 (−0.1 to 0.6) p = 0.21). On average, 33% of eclampsia occurred in women under 20 years old, this varied from 10% in Addis Ababa, Ethiopia to 51% in Zomba, Malawi. 60% occurred in women aged 20–34 and 7% occurred in women aged 35 or older. Discussion Prevalence of eclampsia, and distribution with age, varies between countries. More than 50% of eclampsia occurs in facilities despite magnesium sulphate being widely available." @default.
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- W2893218327 date "2018-10-01" @default.
- W2893218327 modified "2023-10-17" @default.
- W2893218327 title "51. Prevalence of eclampsia in low-resource countries: Secondary analysis of a pragmatic stepped wedge cluster randomised controlled trial" @default.
- W2893218327 doi "https://doi.org/10.1016/j.preghy.2018.08.056" @default.
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