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• W2893220017 abstract "Porcine mammary fatty tissues represent an abundant source of natural biomaterial for generation of breast-specific extracellular matrix (ECM). Here we report the extraction of total ECM proteins from pig breast fatty tissues, the fabrication of hydrogel and porous scaffolds from the extracted ECM proteins, the structural properties of the scaffolds (tissue matrix scaffold, TMS), and the applications of the hydrogel in human mammary epithelial cell spatial cultures for cell surface receptor expression, metabolomics characterization, acini formation, proliferation, migration between different scaffolding compartments, and in vivo tumor formation. This model system provides an additional option for studying human breast diseases such as breast cancer." @default.
• W2893220017 created "2018-10-05" @default.
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• W2893220017 date "2018-09-25" @default.
• W2893220017 modified "2023-09-25" @default.
• W2893220017 title "Porcine Breast Extracellular Matrix Hydrogel for Spatial Tissue Culture" @default.
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• W2893220017 doi "https://doi.org/10.3390/ijms19102912" @default.
• W2893220017 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6213433" @default.
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