FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893237726> ?p ?o ?g. }

• W2893237726 endingPage "e0204918" @default.
• W2893237726 startingPage "e0204918" @default.
• W2893237726 abstract "Purpose To evaluate the potential role of 18F-fluorodeoxyglucose-positron emission tomography/computerized tomography (FDG-PET/CT) for predicting treatment response after radiotherapy (RT) in patients with spinal metastases. Materials and methods A retrospective analysis was performed of 42 patients with spinal metastases who received RT from January 2010 to December 2014. All patients underwent FDG-PET/CT before and after treatment. Changes in metabolic responses, expressed as the maximum, mean, peak standardized uptake values (SUVmax, SUVmean, SUVpeak), metabolic tumor volume (MTV) and total lesion glycolysis (TLG) were analyzed to determine their association with clinical outcomes. Results The median age at the time of spinal metastasis diagnosis was 58 years. Median progression-free survival (PFS) and overall survival after RT were 15 months and 22.4 months, respectively. RT produced a significant decrease in SUVmean (2.27 to 1.41), SUVmax (6.87 to 2.99), SUVpeak (5.75 to 2.33) and TLG (52.84 to 24.17) when compared with the baseline values (p<0.001). The mean pain score decreased from 3.86 before RT to 0.79 after RT (p<0.001). There were significant linear relationships between maximum SUV and pain scores at baseline (r = 0.321, p = 0.038) and after treatment (r = 0.369, p = 0.016) as well as TLG at baseline (r = 0.428, p = 0.005) and after treatment (r = 0.403, p = 0.009). Local progression after treatment was identified in 12 patients (28.6%). Univariate analyses showed that >70% reduction in maximum SUV after treatment was independently associated with good PFS (p = 0.036). Conclusions RT is an effective treatment for patients with spinal metastases, and there were significant changes in PET parameters compared with baseline. The metabolic response measured by SUV and TLG changes in FDG-PET/CT correlated with the clinical outcomes, especially with shorter PFS in patients who had higher residual maximum SUV after treatment." @default.
• W2893237726 created "2018-10-05" @default.
• W2893237726 creator A5021553238 @default.
• W2893237726 creator A5031985823 @default.
• W2893237726 creator A5055301615 @default.
• W2893237726 creator A5057589182 @default.
• W2893237726 date "2018-09-28" @default.
• W2893237726 modified "2023-10-05" @default.
• W2893237726 title "The 18F-FDG PET/CT response to radiotherapy for patients with spinal metastasis correlated with the clinical outcomes" @default.
• W2893237726 cites W1552810603 @default.
• W2893237726 cites W1938447409 @default.
• W2893237726 cites W1964391021 @default.
• W2893237726 cites W1981353983 @default.
• W2893237726 cites W1989645145 @default.
• W2893237726 cites W1993494057 @default.
• W2893237726 cites W2005356522 @default.
• W2893237726 cites W2010526726 @default.
• W2893237726 cites W2018255531 @default.
• W2893237726 cites W2053787128 @default.
• W2893237726 cites W2069641832 @default.
• W2893237726 cites W2073017415 @default.
• W2893237726 cites W2076163094 @default.
• W2893237726 cites W2084874632 @default.
• W2893237726 cites W2090377585 @default.
• W2893237726 cites W2098070070 @default.
• W2893237726 cites W2104302044 @default.
• W2893237726 cites W2115989405 @default.
• W2893237726 cites W2116955161 @default.
• W2893237726 cites W2129180082 @default.
• W2893237726 cites W2155263737 @default.
• W2893237726 cites W2162439819 @default.
• W2893237726 cites W2185554757 @default.
• W2893237726 cites W2220939468 @default.
• W2893237726 cites W2260562219 @default.
• W2893237726 cites W2310555595 @default.
• W2893237726 cites W2411740203 @default.
• W2893237726 cites W2426671653 @default.
• W2893237726 cites W2794491082 @default.
• W2893237726 doi "https://doi.org/10.1371/journal.pone.0204918" @default.
• W2893237726 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6161908" @default.
• W2893237726 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30265736" @default.
• W2893237726 hasPublicationYear "2018" @default.
• W2893237726 type Work @default.
• W2893237726 sameAs 2893237726 @default.
• W2893237726 citedByCount "5" @default.
• W2893237726 countsByYear W28932377262018 @default.
• W2893237726 countsByYear W28932377262019 @default.
• W2893237726 countsByYear W28932377262020 @default.
• W2893237726 countsByYear W28932377262022 @default.
• W2893237726 crossrefType "journal-article" @default.
• W2893237726 hasAuthorship W2893237726A5021553238 @default.
• W2893237726 hasAuthorship W2893237726A5031985823 @default.
• W2893237726 hasAuthorship W2893237726A5055301615 @default.
• W2893237726 hasAuthorship W2893237726A5057589182 @default.
• W2893237726 hasBestOaLocation W28932377261 @default.
• W2893237726 hasConcept C121608353 @default.
• W2893237726 hasConcept C126322002 @default.
• W2893237726 hasConcept C126838900 @default.
• W2893237726 hasConcept C144301174 @default.
• W2893237726 hasConcept C167135981 @default.
• W2893237726 hasConcept C199374082 @default.
• W2893237726 hasConcept C2775842073 @default.
• W2893237726 hasConcept C2777415128 @default.
• W2893237726 hasConcept C2779013556 @default.
• W2893237726 hasConcept C2989005 @default.
• W2893237726 hasConcept C38180746 @default.
• W2893237726 hasConcept C509974204 @default.
• W2893237726 hasConcept C71924100 @default.
• W2893237726 hasConceptScore W2893237726C121608353 @default.
• W2893237726 hasConceptScore W2893237726C126322002 @default.
• W2893237726 hasConceptScore W2893237726C126838900 @default.
• W2893237726 hasConceptScore W2893237726C144301174 @default.
• W2893237726 hasConceptScore W2893237726C167135981 @default.
• W2893237726 hasConceptScore W2893237726C199374082 @default.
• W2893237726 hasConceptScore W2893237726C2775842073 @default.
• W2893237726 hasConceptScore W2893237726C2777415128 @default.
• W2893237726 hasConceptScore W2893237726C2779013556 @default.
• W2893237726 hasConceptScore W2893237726C2989005 @default.
• W2893237726 hasConceptScore W2893237726C38180746 @default.
• W2893237726 hasConceptScore W2893237726C509974204 @default.
• W2893237726 hasConceptScore W2893237726C71924100 @default.
• W2893237726 hasFunder F4320321408 @default.
• W2893237726 hasIssue "9" @default.
• W2893237726 hasLocation W28932377261 @default.
• W2893237726 hasLocation W28932377262 @default.
• W2893237726 hasLocation W28932377263 @default.
• W2893237726 hasLocation W28932377264 @default.
• W2893237726 hasLocation W28932377265 @default.
• W2893237726 hasOpenAccess W2893237726 @default.
• W2893237726 hasPrimaryLocation W28932377261 @default.
• W2893237726 hasRelatedWork W1796991209 @default.
• W2893237726 hasRelatedWork W1911863881 @default.
• W2893237726 hasRelatedWork W1968520296 @default.
• W2893237726 hasRelatedWork W1982187894 @default.
• W2893237726 hasRelatedWork W2083210814 @default.
• W2893237726 hasRelatedWork W2089462794 @default.
• W2893237726 hasRelatedWork W2111347914 @default.
• W2893237726 hasRelatedWork W2117290479 @default.

• next