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- W2893244477 abstract "Cardiac contraction is coordinated by a wave of electrical excitation which propagates through the heart. Combined modelling of electrical and mechanical function of the heart provides the most comprehensive description of cardiac function and is one of the latest trends in cardiac research. The effective numerical modelling of cardiac electromechanics remains a challenge, due to the stiffness of the electrical equations and the global coupling in the mechanical problem. Here we present a short review of the inherent assumptions made when deriving the electromechanical equations, including a general representation for deformation-dependent conduction tensors obeying orthotropic symmetry, and then present an implicit-explicit time-stepping approach that is tailored to solving the cardiac mono- or bidomain equations coupled to electromechanics of the cardiac wall. Our approach allows to find numerical solutions of the electromechanics equations using stable and higher order time integration. Our methods are implemented in a monolithic finite element code GEMS (Ghent Electromechanics Solver) using the PETSc library that is inherently parallelized for use on high-performance computing infrastructure. We tested GEMS on standard benchmark computations and discuss further development of our software." @default.
- W2893244477 created "2018-10-05" @default.
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- W2893244477 date "2018-10-16" @default.
- W2893244477 modified "2023-09-27" @default.
- W2893244477 title "GEMS: A Fully Integrated PETSc-Based Solver for Coupled Cardiac Electromechanics and Bidomain Simulations" @default.
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- W2893244477 doi "https://doi.org/10.3389/fphys.2018.01431" @default.
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