Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893255584> ?p ?o ?g. }
- W2893255584 endingPage "261" @default.
- W2893255584 startingPage "254" @default.
- W2893255584 abstract "ABSTRACT Background and objective Patients with chronic obstructive pulmonary disease (COPD) and chronic hypercapnic respiratory failure (CHRF) characteristically have exercise intolerance and limitations in performing conventional training. Therefore, the aim of this study was to investigate the acute effects of non‐invasive ventilation (NIV) as a supportive tool during exercise in CHRF. Methods Two cycle endurance tests (CET) at 60% of the peak work rate were performed. Patients were randomly assigned to cycle in two conditions: (i) high‐pressure NIV (mean inspiratory positive airway pressure: 27 ± 3 cm H 2 O) along with oxygen supplementation or (ii) control: oxygen‐use only. Transcutaneously measured partial pressure of carbon dioxide (TcPCO 2 ), oxygen saturation and heart rate were continuously recorded. Muscle oxygen availability of intercostal and vastus lateralis muscle was measured during exercise by near‐infrared spectroscopy (NIRS). Results A total of 20 patients with CHRF (forced expiratory volume in 1 s (FEV 1 ): 19 ± 4% predicted, partial pressure of oxygen (PaO 2 ): 55 ± 9 mm Hg, partial pressure of carbon dioxide (PaCO 2 ): 51 ± 7 mm Hg) were recruited in a randomized cross‐over trial. On NIV, COPD patients increased cycle endurance time by 39% compared to oxygen‐use only (663 ± 360 vs 477 ± 249 s, P = 0.013). On NIV, TcPCO 2 was significantly lower at rest (44.9 ± 6.2 vs 50.7 ± 6.6 mm Hg, P < 0.001) and at isotime (50.0 ± 5.5 vs 56.1 ± 6.2 mm Hg, P < 0.001). Oxygen availability in the intercostal muscles remained relatively constant with NIV compared to oxygen‐use only. Although patients cycled longer using NIV, a lower increase in exertional dyspnoea at the end of CET (median increase in Borg‐dyspnoea: 2 vs 4, P = 0.003) was reported. Conclusion NIV with high pressures as add‐on to oxygen supplementation increases cycle endurance time, mitigates exertional dyspnoea and limits exercise‐induced hypercapnia in COPD patients with CHRF." @default.
- W2893255584 created "2018-10-05" @default.
- W2893255584 creator A5004167699 @default.
- W2893255584 creator A5005751035 @default.
- W2893255584 creator A5008405326 @default.
- W2893255584 creator A5012632684 @default.
- W2893255584 creator A5043296538 @default.
- W2893255584 creator A5052200654 @default.
- W2893255584 creator A5059018267 @default.
- W2893255584 creator A5059144923 @default.
- W2893255584 creator A5074366312 @default.
- W2893255584 creator A5091121074 @default.
- W2893255584 date "2018-09-21" @default.
- W2893255584 modified "2023-10-17" @default.
- W2893255584 title "High‐pressure non‐invasive ventilation during exercise in COPD patients with chronic hypercapnic respiratory failure: A randomized, controlled, cross‐over trial" @default.
- W2893255584 cites W1978350087 @default.
- W2893255584 cites W1982259662 @default.
- W2893255584 cites W1986804427 @default.
- W2893255584 cites W1999435877 @default.
- W2893255584 cites W2004008756 @default.
- W2893255584 cites W2047598968 @default.
- W2893255584 cites W2098620423 @default.
- W2893255584 cites W2099516153 @default.
- W2893255584 cites W2099769151 @default.
- W2893255584 cites W2101918266 @default.
- W2893255584 cites W2103910088 @default.
- W2893255584 cites W2104578732 @default.
- W2893255584 cites W2106651585 @default.
- W2893255584 cites W2107752645 @default.
- W2893255584 cites W2114850937 @default.
- W2893255584 cites W2115817277 @default.
- W2893255584 cites W2119726594 @default.
- W2893255584 cites W2135178320 @default.
- W2893255584 cites W2135743707 @default.
- W2893255584 cites W2151029963 @default.
- W2893255584 cites W2152912650 @default.
- W2893255584 cites W2154218475 @default.
- W2893255584 cites W2155149248 @default.
- W2893255584 cites W2155567073 @default.
- W2893255584 cites W2159603976 @default.
- W2893255584 cites W2167168387 @default.
- W2893255584 cites W2571885823 @default.
- W2893255584 cites W2603214344 @default.
- W2893255584 cites W2615946421 @default.
- W2893255584 cites W2758911419 @default.
- W2893255584 cites W2769567982 @default.
- W2893255584 cites W3082163909 @default.
- W2893255584 cites W4300777336 @default.
- W2893255584 doi "https://doi.org/10.1111/resp.13399" @default.
- W2893255584 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30242790" @default.
- W2893255584 hasPublicationYear "2018" @default.
- W2893255584 type Work @default.
- W2893255584 sameAs 2893255584 @default.
- W2893255584 citedByCount "29" @default.
- W2893255584 countsByYear W28932555842018 @default.
- W2893255584 countsByYear W28932555842019 @default.
- W2893255584 countsByYear W28932555842020 @default.
- W2893255584 countsByYear W28932555842021 @default.
- W2893255584 countsByYear W28932555842022 @default.
- W2893255584 countsByYear W28932555842023 @default.
- W2893255584 crossrefType "journal-article" @default.
- W2893255584 hasAuthorship W2893255584A5004167699 @default.
- W2893255584 hasAuthorship W2893255584A5005751035 @default.
- W2893255584 hasAuthorship W2893255584A5008405326 @default.
- W2893255584 hasAuthorship W2893255584A5012632684 @default.
- W2893255584 hasAuthorship W2893255584A5043296538 @default.
- W2893255584 hasAuthorship W2893255584A5052200654 @default.
- W2893255584 hasAuthorship W2893255584A5059018267 @default.
- W2893255584 hasAuthorship W2893255584A5059144923 @default.
- W2893255584 hasAuthorship W2893255584A5074366312 @default.
- W2893255584 hasAuthorship W2893255584A5091121074 @default.
- W2893255584 hasBestOaLocation W28932555841 @default.
- W2893255584 hasConcept C126322002 @default.
- W2893255584 hasConcept C127413603 @default.
- W2893255584 hasConcept C164705383 @default.
- W2893255584 hasConcept C178790620 @default.
- W2893255584 hasConcept C185592680 @default.
- W2893255584 hasConcept C200457457 @default.
- W2893255584 hasConcept C2776780178 @default.
- W2893255584 hasConcept C42219234 @default.
- W2893255584 hasConcept C534529494 @default.
- W2893255584 hasConcept C540031477 @default.
- W2893255584 hasConcept C71924100 @default.
- W2893255584 hasConcept C76538665 @default.
- W2893255584 hasConcept C78519656 @default.
- W2893255584 hasConcept C79959777 @default.
- W2893255584 hasConceptScore W2893255584C126322002 @default.
- W2893255584 hasConceptScore W2893255584C127413603 @default.
- W2893255584 hasConceptScore W2893255584C164705383 @default.
- W2893255584 hasConceptScore W2893255584C178790620 @default.
- W2893255584 hasConceptScore W2893255584C185592680 @default.
- W2893255584 hasConceptScore W2893255584C200457457 @default.
- W2893255584 hasConceptScore W2893255584C2776780178 @default.
- W2893255584 hasConceptScore W2893255584C42219234 @default.
- W2893255584 hasConceptScore W2893255584C534529494 @default.
- W2893255584 hasConceptScore W2893255584C540031477 @default.
- W2893255584 hasConceptScore W2893255584C71924100 @default.
- W2893255584 hasConceptScore W2893255584C76538665 @default.