Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893264710> ?p ?o ?g. }
- W2893264710 endingPage "43" @default.
- W2893264710 startingPage "43" @default.
- W2893264710 abstract "Subepithelial lesions (SELs) of the upper part of the digestive tract are rare, and it can be difficult to characterize them. Recently, contrast-enhanced endosonography (EUS) and elastometry have been reported as useful adjuncts to EUS and EUS-guided fine needle aspiration (EUS-FNA) in cases of pancreatic mass and lymph node involvement. The aim of this retrospective analysis was to evaluate whether contrast-enhanced EUS can discriminate benign submucosal lesions from malignant ones. We describe our retrospective experience using the contrast agent SonoVue® (Bracco Imaging, Milan, Italy) in an attempt to increase the diagnostic yield.Between May 2011 and September 2014, 14 patients (5 men, 9 women; median age 64 years, range 31-80 years) with SELs of the stomach or esophagus underwent EUS with SonoVue® (low mechanical index). There were 3 esophageal lesions and 11 gastric lesions. Mean size of the lesions was 30 mm (range 11-50 mm). They were discovered after anemia (n = 5), dysphagia (n = 1), and pain (n = 4) and during follow-up for resected gastrointestinal stromal tumors (GISTs) (n = 1) and a standard upper gastrointestinal endoscopy (n = 3). On endoscopic sonograms, 10 of these lesions were hypoechoic and located in the fourth layer (muscularis), and 4 were in the second or third layer (mucosa and submucosa). Contrast enhancement was assessed in the early phase (after several seconds) and late phase (>30 seconds); a final diagnosis was made based on the findings of EUS-FNA using a 19-gauge ProCore (Cook Medical, Bloomington, IN) (n = 9) or 22-gauge FNA system (Cook Medical) (n = 1), the resected specimen (n = 3), or deep biopsy (n = 1). Different immunostaining was used in the pathologic studies (RNA was analyzed later using the C-kit, CD-117, CD-34, desmin, DOG-1, α-smooth actin, caldesmon, PS-100, and Ki-67 antibodies).Final diagnoses were leiomyoma (n = 4), GIST (n = 5), schwannoma (n = 1), inflammatory tumor of Helvig (n = 1), pancreas rest (n = 2), and fibrosis (n = 1). No complications occurred. All 5 GISTs showed enhancement in the early and late phases, whereas the 8 remaining lesions did not show any enhancement. Only 1 leiomyoma showed heterogeneous enhancement.The monocentric and retrospective study design and small number of patients.In cases of SELs of the stomach or esophagus, SonoVue® could be a complementary tool to endosonography to differentiate GISTs (early and clear enhancement) from other SELs (few or no enhancement), such as leiomyomas or pancreatic rest. These results are similar to those of the few, small studies published on this topic, but more studies with a larger number of patients are needed to confirm these findings." @default.
- W2893264710 created "2018-10-05" @default.
- W2893264710 creator A5001651792 @default.
- W2893264710 creator A5001801422 @default.
- W2893264710 creator A5017732235 @default.
- W2893264710 creator A5019925832 @default.
- W2893264710 creator A5019977580 @default.
- W2893264710 creator A5026933339 @default.
- W2893264710 creator A5043035411 @default.
- W2893264710 creator A5044055865 @default.
- W2893264710 creator A5047410221 @default.
- W2893264710 creator A5082710196 @default.
- W2893264710 date "2019-01-01" @default.
- W2893264710 modified "2023-10-16" @default.
- W2893264710 title "Characterization of subepithelial lesions of the stomach and esophagus by contrast-enhanced EUS: A retrospective study" @default.
- W2893264710 cites W1486916105 @default.
- W2893264710 cites W1516279414 @default.
- W2893264710 cites W1971976492 @default.
- W2893264710 cites W1972138578 @default.
- W2893264710 cites W1976570935 @default.
- W2893264710 cites W1979366041 @default.
- W2893264710 cites W1981021447 @default.
- W2893264710 cites W1982205680 @default.
- W2893264710 cites W1986678391 @default.
- W2893264710 cites W1998275242 @default.
- W2893264710 cites W2013316786 @default.
- W2893264710 cites W2017122567 @default.
- W2893264710 cites W2021386457 @default.
- W2893264710 cites W2024226476 @default.
- W2893264710 cites W2024309720 @default.
- W2893264710 cites W2026172424 @default.
- W2893264710 cites W2029155157 @default.
- W2893264710 cites W2034475200 @default.
- W2893264710 cites W2053625245 @default.
- W2893264710 cites W2053837180 @default.
- W2893264710 cites W2054741927 @default.
- W2893264710 cites W2055325305 @default.
- W2893264710 cites W2061690773 @default.
- W2893264710 cites W2073008958 @default.
- W2893264710 cites W2087570543 @default.
- W2893264710 cites W2092741408 @default.
- W2893264710 cites W2097426792 @default.
- W2893264710 cites W2135416771 @default.
- W2893264710 cites W33167681 @default.
- W2893264710 cites W4250750324 @default.
- W2893264710 cites W2021519563 @default.
- W2893264710 doi "https://doi.org/10.4103/eus.eus_89_17" @default.
- W2893264710 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6400084" @default.
- W2893264710 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30264741" @default.
- W2893264710 hasPublicationYear "2019" @default.
- W2893264710 type Work @default.
- W2893264710 sameAs 2893264710 @default.
- W2893264710 citedByCount "37" @default.
- W2893264710 countsByYear W28932647102019 @default.
- W2893264710 countsByYear W28932647102020 @default.
- W2893264710 countsByYear W28932647102021 @default.
- W2893264710 countsByYear W28932647102022 @default.
- W2893264710 countsByYear W28932647102023 @default.
- W2893264710 crossrefType "journal-article" @default.
- W2893264710 hasAuthorship W2893264710A5001651792 @default.
- W2893264710 hasAuthorship W2893264710A5001801422 @default.
- W2893264710 hasAuthorship W2893264710A5017732235 @default.
- W2893264710 hasAuthorship W2893264710A5019925832 @default.
- W2893264710 hasAuthorship W2893264710A5019977580 @default.
- W2893264710 hasAuthorship W2893264710A5026933339 @default.
- W2893264710 hasAuthorship W2893264710A5043035411 @default.
- W2893264710 hasAuthorship W2893264710A5044055865 @default.
- W2893264710 hasAuthorship W2893264710A5047410221 @default.
- W2893264710 hasAuthorship W2893264710A5082710196 @default.
- W2893264710 hasBestOaLocation W28932647102 @default.
- W2893264710 hasConcept C126322002 @default.
- W2893264710 hasConcept C126838900 @default.
- W2893264710 hasConcept C142724271 @default.
- W2893264710 hasConcept C167135981 @default.
- W2893264710 hasConcept C2775934546 @default.
- W2893264710 hasConcept C2776170712 @default.
- W2893264710 hasConcept C2777819096 @default.
- W2893264710 hasConcept C2778451229 @default.
- W2893264710 hasConcept C2779052585 @default.
- W2893264710 hasConcept C2779422922 @default.
- W2893264710 hasConcept C2780390042 @default.
- W2893264710 hasConcept C2780596822 @default.
- W2893264710 hasConcept C2780849966 @default.
- W2893264710 hasConcept C3017397796 @default.
- W2893264710 hasConcept C71924100 @default.
- W2893264710 hasConcept C90924648 @default.
- W2893264710 hasConceptScore W2893264710C126322002 @default.
- W2893264710 hasConceptScore W2893264710C126838900 @default.
- W2893264710 hasConceptScore W2893264710C142724271 @default.
- W2893264710 hasConceptScore W2893264710C167135981 @default.
- W2893264710 hasConceptScore W2893264710C2775934546 @default.
- W2893264710 hasConceptScore W2893264710C2776170712 @default.
- W2893264710 hasConceptScore W2893264710C2777819096 @default.
- W2893264710 hasConceptScore W2893264710C2778451229 @default.
- W2893264710 hasConceptScore W2893264710C2779052585 @default.
- W2893264710 hasConceptScore W2893264710C2779422922 @default.
- W2893264710 hasConceptScore W2893264710C2780390042 @default.
- W2893264710 hasConceptScore W2893264710C2780596822 @default.