FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893295570> ?p ?o ?g. }

• W2893295570 endingPage "241" @default.
• W2893295570 startingPage "231" @default.
• W2893295570 abstract "Diabetes is associated with poor cardiovascular outcomes, and insulin-treated patients usually have a worse prognosis than non-insulin-treated subjects. The relationship between insulin treatment and outcomes in high-risk myocardial infarction patients has not been described in a large dataset.To investigate the association between insulin-treated diabetes and long-term cardiovascular outcomes in patients with high-risk myocardial infarction, we used adjusted Cox models to compare cardiovascular mortality and hospitalisation among 28,771 patients grouped by diabetes status and insulin treatment from four randomised clinical trials (VALIANT, EPHESUS, OPTIMAAL, CAPRICORN) of acute myocardial infarction complicated by heart failure and/or left ventricular systolic dysfunction.After an approximately 2-year follow-up, patients with no diabetes (21,386 subjects, 74.3%), non-insulin-treated diabetes (4977 patients, 17.3%) and insulin-treated diabetes (2409 subjects, 8.4%) had an incremental yearly mortality risk (15.8%, 21.3% and 28.1%, respectively). Insulin-treated diabetes patients presented with a higher cardiovascular burden and comorbidities. After adjustment for 18 baseline covariates, patients with non-insulin-treated and insulin-treated diabetes were at higher risk of cardiovascular death (hazard ratio (HR) 1.25, 95% confidence interval (CI) 1.13-1.38 and HR 1.49, 95% CI 1.31-1.69, respectively; P for comparison of non-insulin-treated vs. insulin-treated diabetes =0.016) and cardiovascular hospitalisation (HR 1.33, 95% CI 1.25-1.41 and HR 1.16, 95% CI 1.11-1.22, respectively) compared to patients without diabetes. These results remained consistent after further adjustment for medications and left ventricular ejection fraction.Insulin-treated diabetes patients had higher event rates than diabetes patients taking oral treatments and patients without diabetes. However, insulin-treated diabetes patients had more comorbidities and atherosclerotic disease, precluding any causality suggestion between insulin treatment and outcomes. This high-risk population may require specific and/or more intense cardiovascular protective therapies." @default.
• W2893295570 created "2018-10-05" @default.
• W2893295570 creator A5001704230 @default.
• W2893295570 creator A5008530481 @default.
• W2893295570 creator A5017349008 @default.
• W2893295570 creator A5031560506 @default.
• W2893295570 creator A5036821495 @default.
• W2893295570 creator A5045495581 @default.
• W2893295570 creator A5048119987 @default.
• W2893295570 creator A5048345767 @default.
• W2893295570 creator A5048450888 @default.
• W2893295570 creator A5081791142 @default.
• W2893295570 date "2018-09-27" @default.
• W2893295570 modified "2023-10-16" @default.
• W2893295570 title "Editor’s Choice- Impact of insulin-treated diabetes on cardiovascular outcomes following high-risk myocardial infarction" @default.
• W2893295570 cites W1553224595 @default.
• W2893295570 cites W1579811715 @default.
• W2893295570 cites W1908289777 @default.
• W2893295570 cites W1932115126 @default.
• W2893295570 cites W1965569440 @default.
• W2893295570 cites W1975663485 @default.
• W2893295570 cites W1981569117 @default.
• W2893295570 cites W1982199889 @default.
• W2893295570 cites W2021011733 @default.
• W2893295570 cites W2044094474 @default.
• W2893295570 cites W2065833280 @default.
• W2893295570 cites W2112920839 @default.
• W2893295570 cites W2126495538 @default.
• W2893295570 cites W2127854619 @default.
• W2893295570 cites W2136642260 @default.
• W2893295570 cites W2142980653 @default.
• W2893295570 cites W2146264128 @default.
• W2893295570 cites W21478844 @default.
• W2893295570 cites W2152094259 @default.
• W2893295570 cites W2155121555 @default.
• W2893295570 cites W2161201373 @default.
• W2893295570 cites W2167761545 @default.
• W2893295570 cites W2168907840 @default.
• W2893295570 cites W2194995290 @default.
• W2893295570 cites W2282578582 @default.
• W2893295570 cites W2308410366 @default.
• W2893295570 cites W2325706434 @default.
• W2893295570 cites W2425644022 @default.
• W2893295570 cites W2519156390 @default.
• W2893295570 cites W2582230608 @default.
• W2893295570 cites W2584897655 @default.
• W2893295570 cites W2602270570 @default.
• W2893295570 cites W2612003085 @default.
• W2893295570 cites W2734772485 @default.
• W2893295570 cites W2766027236 @default.
• W2893295570 cites W2789820915 @default.
• W2893295570 cites W2792867832 @default.
• W2893295570 doi "https://doi.org/10.1177/2048872618803701" @default.
• W2893295570 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30259764" @default.
• W2893295570 hasPublicationYear "2018" @default.
• W2893295570 type Work @default.
• W2893295570 sameAs 2893295570 @default.
• W2893295570 citedByCount "23" @default.
• W2893295570 countsByYear W28932955702019 @default.
• W2893295570 countsByYear W28932955702020 @default.
• W2893295570 countsByYear W28932955702021 @default.
• W2893295570 countsByYear W28932955702022 @default.
• W2893295570 countsByYear W28932955702023 @default.
• W2893295570 crossrefType "journal-article" @default.
• W2893295570 hasAuthorship W2893295570A5001704230 @default.
• W2893295570 hasAuthorship W2893295570A5008530481 @default.
• W2893295570 hasAuthorship W2893295570A5017349008 @default.
• W2893295570 hasAuthorship W2893295570A5031560506 @default.
• W2893295570 hasAuthorship W2893295570A5036821495 @default.
• W2893295570 hasAuthorship W2893295570A5045495581 @default.
• W2893295570 hasAuthorship W2893295570A5048119987 @default.
• W2893295570 hasAuthorship W2893295570A5048345767 @default.
• W2893295570 hasAuthorship W2893295570A5048450888 @default.
• W2893295570 hasAuthorship W2893295570A5081791142 @default.
• W2893295570 hasBestOaLocation W28932955701 @default.
• W2893295570 hasConcept C126322002 @default.
• W2893295570 hasConcept C134018914 @default.
• W2893295570 hasConcept C164705383 @default.
• W2893295570 hasConcept C207103383 @default.
• W2893295570 hasConcept C2777180221 @default.
• W2893295570 hasConcept C2778198053 @default.
• W2893295570 hasConcept C2779306644 @default.
• W2893295570 hasConcept C44249647 @default.
• W2893295570 hasConcept C500558357 @default.
• W2893295570 hasConcept C50382708 @default.
• W2893295570 hasConcept C555293320 @default.
• W2893295570 hasConcept C71924100 @default.
• W2893295570 hasConceptScore W2893295570C126322002 @default.
• W2893295570 hasConceptScore W2893295570C134018914 @default.
• W2893295570 hasConceptScore W2893295570C164705383 @default.
• W2893295570 hasConceptScore W2893295570C207103383 @default.
• W2893295570 hasConceptScore W2893295570C2777180221 @default.
• W2893295570 hasConceptScore W2893295570C2778198053 @default.
• W2893295570 hasConceptScore W2893295570C2779306644 @default.
• W2893295570 hasConceptScore W2893295570C44249647 @default.
• W2893295570 hasConceptScore W2893295570C500558357 @default.
• W2893295570 hasConceptScore W2893295570C50382708 @default.
• W2893295570 hasConceptScore W2893295570C555293320 @default.

• next