Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893321897> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2893321897 endingPage "800" @default.
- W2893321897 startingPage "795" @default.
- W2893321897 abstract "Several known stimulators, including angiotensin II, potassium ions, serotonin and ACTH, act directly on the zona glomerulosa of the rat adrenal cortex during short-term incubation experiments. They rapidly enhance an early biosynthetic step involved in the conversion of cholesterol to pregnenolone. The steroidogenic response elicited by these agents depends on the activity of the enzymes necessary for the final stages of aldosterone biosynthesis, in particular the 18-hydroxylation of corticosterone. The activity of these enzymes is in turn regulated by unknown mediators, which act in response to alterations in sodium and potassium balance. According to indirect evidence, the serum potassium appears to be an important but not the only regulator. Angiotensin II and serotonin may also have a long-term stimulating effect on the final steps of aldosterone biosynthesis. By contrast, treatment of rats with ACTH for a few days causes a marked decrease in the conversion of tritiated corticosterone to 18-hydroxycorticosterone and aldosterone." @default.
- W2893321897 created "2018-10-05" @default.
- W2893321897 creator A5028895212 @default.
- W2893321897 creator A5071660959 @default.
- W2893321897 date "1975-01-01" @default.
- W2893321897 modified "2023-09-27" @default.
- W2893321897 title "MULTIFACTORIAL REGULATION OF THE FINAL STEPS OF ALDOSTERONE BIOSYNTHESIS IN THE RAT**Supported by Grant No. 3.325.70 of the Swiss National Foundation for Scientific Research." @default.
- W2893321897 cites W1970253435 @default.
- W2893321897 cites W1984893030 @default.
- W2893321897 cites W1988004493 @default.
- W2893321897 cites W2002134229 @default.
- W2893321897 cites W2020126514 @default.
- W2893321897 cites W2025802776 @default.
- W2893321897 cites W2044404050 @default.
- W2893321897 cites W2049913826 @default.
- W2893321897 cites W2089546849 @default.
- W2893321897 cites W2092088194 @default.
- W2893321897 cites W2112477277 @default.
- W2893321897 cites W2157932358 @default.
- W2893321897 cites W2163696584 @default.
- W2893321897 doi "https://doi.org/10.1016/b978-0-08-019709-8.50013-7" @default.
- W2893321897 hasPublicationYear "1975" @default.
- W2893321897 type Work @default.
- W2893321897 sameAs 2893321897 @default.
- W2893321897 citedByCount "0" @default.
- W2893321897 crossrefType "book-chapter" @default.
- W2893321897 hasAuthorship W2893321897A5028895212 @default.
- W2893321897 hasAuthorship W2893321897A5071660959 @default.
- W2893321897 hasConcept C104317684 @default.
- W2893321897 hasConcept C126322002 @default.
- W2893321897 hasConcept C134018914 @default.
- W2893321897 hasConcept C178790620 @default.
- W2893321897 hasConcept C181199279 @default.
- W2893321897 hasConcept C185592680 @default.
- W2893321897 hasConcept C2777977426 @default.
- W2893321897 hasConcept C2778525890 @default.
- W2893321897 hasConcept C2780178468 @default.
- W2893321897 hasConcept C2780193516 @default.
- W2893321897 hasConcept C2780352252 @default.
- W2893321897 hasConcept C2780902042 @default.
- W2893321897 hasConcept C2908929049 @default.
- W2893321897 hasConcept C517785266 @default.
- W2893321897 hasConcept C537181965 @default.
- W2893321897 hasConcept C553450214 @default.
- W2893321897 hasConcept C55493867 @default.
- W2893321897 hasConcept C6929976 @default.
- W2893321897 hasConcept C71315377 @default.
- W2893321897 hasConcept C71924100 @default.
- W2893321897 hasConcept C84393581 @default.
- W2893321897 hasConcept C86803240 @default.
- W2893321897 hasConceptScore W2893321897C104317684 @default.
- W2893321897 hasConceptScore W2893321897C126322002 @default.
- W2893321897 hasConceptScore W2893321897C134018914 @default.
- W2893321897 hasConceptScore W2893321897C178790620 @default.
- W2893321897 hasConceptScore W2893321897C181199279 @default.
- W2893321897 hasConceptScore W2893321897C185592680 @default.
- W2893321897 hasConceptScore W2893321897C2777977426 @default.
- W2893321897 hasConceptScore W2893321897C2778525890 @default.
- W2893321897 hasConceptScore W2893321897C2780178468 @default.
- W2893321897 hasConceptScore W2893321897C2780193516 @default.
- W2893321897 hasConceptScore W2893321897C2780352252 @default.
- W2893321897 hasConceptScore W2893321897C2780902042 @default.
- W2893321897 hasConceptScore W2893321897C2908929049 @default.
- W2893321897 hasConceptScore W2893321897C517785266 @default.
- W2893321897 hasConceptScore W2893321897C537181965 @default.
- W2893321897 hasConceptScore W2893321897C553450214 @default.
- W2893321897 hasConceptScore W2893321897C55493867 @default.
- W2893321897 hasConceptScore W2893321897C6929976 @default.
- W2893321897 hasConceptScore W2893321897C71315377 @default.
- W2893321897 hasConceptScore W2893321897C71924100 @default.
- W2893321897 hasConceptScore W2893321897C84393581 @default.
- W2893321897 hasConceptScore W2893321897C86803240 @default.
- W2893321897 hasLocation W28933218971 @default.
- W2893321897 hasOpenAccess W2893321897 @default.
- W2893321897 hasPrimaryLocation W28933218971 @default.
- W2893321897 hasRelatedWork W1970273149 @default.
- W2893321897 hasRelatedWork W1998134099 @default.
- W2893321897 hasRelatedWork W2006202112 @default.
- W2893321897 hasRelatedWork W2017346924 @default.
- W2893321897 hasRelatedWork W2025802776 @default.
- W2893321897 hasRelatedWork W2037220744 @default.
- W2893321897 hasRelatedWork W2042864339 @default.
- W2893321897 hasRelatedWork W2125601140 @default.
- W2893321897 hasRelatedWork W2894169634 @default.
- W2893321897 hasRelatedWork W4234160658 @default.
- W2893321897 isParatext "false" @default.
- W2893321897 isRetracted "false" @default.
- W2893321897 magId "2893321897" @default.
- W2893321897 workType "book-chapter" @default.