Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893329689> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W2893329689 endingPage "S88" @default.
- W2893329689 startingPage "S88" @default.
- W2893329689 abstract "Chondroitin sulfate (CS) is a relevant family of polysaccharides that participates in a large variety of biological events that are related to neural processes by regulating various growth factors through the pattern and degree of sulfation of the polysaccharide. However, their own complexity makes their optimization for biomedical applications a difficult undertaking. Thus, a different perspective has to be taken. Herein, we show that the particular sulfate distribution within the disaccharide repeating-unit plays a key role in the binding of growth factors (GFs). In particular, this disposition modulates the surface charge of the helical structure that, interestingly, has a significant influence on the binding capacity of CSs with several GFs. This fact should be carefully considered in the design of new ligands with improved activity as GFs ligands." @default.
- W2893329689 created "2018-10-05" @default.
- W2893329689 creator A5006188708 @default.
- W2893329689 creator A5010339137 @default.
- W2893329689 creator A5048276688 @default.
- W2893329689 creator A5067316205 @default.
- W2893329689 creator A5075176515 @default.
- W2893329689 date "2018-10-01" @default.
- W2893329689 modified "2023-09-26" @default.
- W2893329689 title "Physiological characterization of metabolically engineered E. coli K4 strains with improved pathways for capsular polysaccharide biosynthesis" @default.
- W2893329689 doi "https://doi.org/10.1016/j.nbt.2018.05.935" @default.
- W2893329689 hasPublicationYear "2018" @default.
- W2893329689 type Work @default.
- W2893329689 sameAs 2893329689 @default.
- W2893329689 citedByCount "0" @default.
- W2893329689 crossrefType "journal-article" @default.
- W2893329689 hasAuthorship W2893329689A5006188708 @default.
- W2893329689 hasAuthorship W2893329689A5010339137 @default.
- W2893329689 hasAuthorship W2893329689A5048276688 @default.
- W2893329689 hasAuthorship W2893329689A5067316205 @default.
- W2893329689 hasAuthorship W2893329689A5075176515 @default.
- W2893329689 hasConcept C100817775 @default.
- W2893329689 hasConcept C104317684 @default.
- W2893329689 hasConcept C153074725 @default.
- W2893329689 hasConcept C155138218 @default.
- W2893329689 hasConcept C185592680 @default.
- W2893329689 hasConcept C2777346074 @default.
- W2893329689 hasConcept C2779553658 @default.
- W2893329689 hasConcept C553450214 @default.
- W2893329689 hasConcept C55493867 @default.
- W2893329689 hasConcept C70721500 @default.
- W2893329689 hasConcept C86803240 @default.
- W2893329689 hasConceptScore W2893329689C100817775 @default.
- W2893329689 hasConceptScore W2893329689C104317684 @default.
- W2893329689 hasConceptScore W2893329689C153074725 @default.
- W2893329689 hasConceptScore W2893329689C155138218 @default.
- W2893329689 hasConceptScore W2893329689C185592680 @default.
- W2893329689 hasConceptScore W2893329689C2777346074 @default.
- W2893329689 hasConceptScore W2893329689C2779553658 @default.
- W2893329689 hasConceptScore W2893329689C553450214 @default.
- W2893329689 hasConceptScore W2893329689C55493867 @default.
- W2893329689 hasConceptScore W2893329689C70721500 @default.
- W2893329689 hasConceptScore W2893329689C86803240 @default.
- W2893329689 hasLocation W28933296891 @default.
- W2893329689 hasOpenAccess W2893329689 @default.
- W2893329689 hasPrimaryLocation W28933296891 @default.
- W2893329689 hasRelatedWork W1985844109 @default.
- W2893329689 hasRelatedWork W2001103457 @default.
- W2893329689 hasRelatedWork W2009317046 @default.
- W2893329689 hasRelatedWork W2069912787 @default.
- W2893329689 hasRelatedWork W2414975270 @default.
- W2893329689 hasRelatedWork W2497831928 @default.
- W2893329689 hasRelatedWork W2739100764 @default.
- W2893329689 hasRelatedWork W4235019470 @default.
- W2893329689 hasRelatedWork W51856668 @default.
- W2893329689 hasRelatedWork W55321852 @default.
- W2893329689 hasVolume "44" @default.
- W2893329689 isParatext "false" @default.
- W2893329689 isRetracted "false" @default.
- W2893329689 magId "2893329689" @default.
- W2893329689 workType "article" @default.