Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893331044> ?p ?o ?g. }
- W2893331044 endingPage "4773" @default.
- W2893331044 startingPage "4764" @default.
- W2893331044 abstract "Abstract A metal‐free and oxidant‐free method for the one‐pot preparation of quinazolin‐4( 3H )‐ones enabled by electrochemical oxidation is described. Together with 2‐aminobenzamides, a variety of aldehydes were successfully applied to an acid‐catalyzed annulation and direct anodic oxidation cascade, affording structurally diverse quinazoline‐4( 3H )‐ones in good to excellent yields. Additionally, certain alcohols can be directly applied instead of the corresponding aldehydes to achieve the same final products with the assistance of an electrolysis mediator (TEMPO). The reaction mechanism was carefully examined and the results strongly suggest that the direct and indirect oxidation go through different pathways. As an efficient and environmentally friendly access to a broad range of quinazolin‐4( 3H )‐ones, the synthetic utility of this method was demonstrated by gram‐scale operation, as well as the preparation of bioactive mackinazolinone and truncated erlotinib. magnified image" @default.
- W2893331044 created "2018-10-05" @default.
- W2893331044 creator A5024291508 @default.
- W2893331044 creator A5062170722 @default.
- W2893331044 creator A5068271085 @default.
- W2893331044 creator A5070878079 @default.
- W2893331044 creator A5070937284 @default.
- W2893331044 creator A5086133993 @default.
- W2893331044 date "2018-10-30" @default.
- W2893331044 modified "2023-09-30" @default.
- W2893331044 title "One-Pot Synthesis of Quinazolin-4(3<i>H</i>)-ones through Anodic Oxidation and the Related Mechanistic Studies" @default.
- W2893331044 cites W1803312300 @default.
- W2893331044 cites W1827256991 @default.
- W2893331044 cites W1865931177 @default.
- W2893331044 cites W1964430808 @default.
- W2893331044 cites W1969428644 @default.
- W2893331044 cites W1976508666 @default.
- W2893331044 cites W1979194751 @default.
- W2893331044 cites W1981175120 @default.
- W2893331044 cites W1985096884 @default.
- W2893331044 cites W1999670673 @default.
- W2893331044 cites W2008439477 @default.
- W2893331044 cites W2013480765 @default.
- W2893331044 cites W2028243349 @default.
- W2893331044 cites W2029828534 @default.
- W2893331044 cites W2030416361 @default.
- W2893331044 cites W2030561760 @default.
- W2893331044 cites W2047812593 @default.
- W2893331044 cites W2051259025 @default.
- W2893331044 cites W2064269661 @default.
- W2893331044 cites W2068206113 @default.
- W2893331044 cites W2069135570 @default.
- W2893331044 cites W2084053490 @default.
- W2893331044 cites W2088624554 @default.
- W2893331044 cites W2089723968 @default.
- W2893331044 cites W2097881422 @default.
- W2893331044 cites W2103820855 @default.
- W2893331044 cites W2111557113 @default.
- W2893331044 cites W2128289923 @default.
- W2893331044 cites W2138690604 @default.
- W2893331044 cites W2151492581 @default.
- W2893331044 cites W2165682602 @default.
- W2893331044 cites W2167838288 @default.
- W2893331044 cites W2296444199 @default.
- W2893331044 cites W2319719194 @default.
- W2893331044 cites W2320212436 @default.
- W2893331044 cites W2322156371 @default.
- W2893331044 cites W2327425901 @default.
- W2893331044 cites W2332938021 @default.
- W2893331044 cites W2347015396 @default.
- W2893331044 cites W2407203495 @default.
- W2893331044 cites W2474794377 @default.
- W2893331044 cites W2498693036 @default.
- W2893331044 cites W2512343361 @default.
- W2893331044 cites W2521380261 @default.
- W2893331044 cites W2523201786 @default.
- W2893331044 cites W2594966673 @default.
- W2893331044 cites W2605444656 @default.
- W2893331044 cites W2747026311 @default.
- W2893331044 cites W2760195322 @default.
- W2893331044 cites W2761551323 @default.
- W2893331044 cites W2777951417 @default.
- W2893331044 cites W2783065769 @default.
- W2893331044 cites W2949065977 @default.
- W2893331044 cites W2949467973 @default.
- W2893331044 cites W2950071489 @default.
- W2893331044 cites W2950177245 @default.
- W2893331044 cites W2951116386 @default.
- W2893331044 cites W2951338140 @default.
- W2893331044 cites W2952438929 @default.
- W2893331044 cites W2952948453 @default.
- W2893331044 cites W2953330100 @default.
- W2893331044 cites W2993095857 @default.
- W2893331044 doi "https://doi.org/10.1002/adsc.201800927" @default.
- W2893331044 hasPublicationYear "2018" @default.
- W2893331044 type Work @default.
- W2893331044 sameAs 2893331044 @default.
- W2893331044 citedByCount "29" @default.
- W2893331044 countsByYear W28933310442019 @default.
- W2893331044 countsByYear W28933310442020 @default.
- W2893331044 countsByYear W28933310442021 @default.
- W2893331044 countsByYear W28933310442022 @default.
- W2893331044 countsByYear W28933310442023 @default.
- W2893331044 crossrefType "journal-article" @default.
- W2893331044 hasAuthorship W2893331044A5024291508 @default.
- W2893331044 hasAuthorship W2893331044A5062170722 @default.
- W2893331044 hasAuthorship W2893331044A5068271085 @default.
- W2893331044 hasAuthorship W2893331044A5070878079 @default.
- W2893331044 hasAuthorship W2893331044A5070937284 @default.
- W2893331044 hasAuthorship W2893331044A5086133993 @default.
- W2893331044 hasConcept C147789679 @default.
- W2893331044 hasConcept C161790260 @default.
- W2893331044 hasConcept C163127949 @default.
- W2893331044 hasConcept C171534860 @default.
- W2893331044 hasConcept C17525397 @default.
- W2893331044 hasConcept C178790620 @default.
- W2893331044 hasConcept C185592680 @default.
- W2893331044 hasConcept C18903297 @default.