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- W2893364020 endingPage "34" @default.
- W2893364020 startingPage "11" @default.
- W2893364020 abstract "Patients with atrial fibrillation are known to be at significant risk of stroke. Preventative therapy with an anticoagulant is typically indicated based on patient risk factors. Anticoagulant therapy for decades has consisted of only vitamin K antagonists, such as warfarin, but additional options are now available. These include the direct thrombin inhibitor dabigatran and the direct factor Xa inhibitors rivaroxaban, apixaban, and edoxaban. Warfarin has complex pharmacology, pharmacokinetics, and pharmacodynamics. There are also a number of drug interactions and food interactions that must be considered with the use of warfarin. Direct oral anticoagulants provide a different pharmacology to providing their anticoagulant effect. The agents currently available have differences in pharmacology, pharmacokinetics, and drug interaction potential. Regardless of the anticoagulant selected for the patient, clinicians must have a firm foundation in the pharmacology, pharmacokinetics, dosing, and knowledge of drug interactions to provide optimal care to their patients." @default.
- W2893364020 created "2018-10-05" @default.
- W2893364020 creator A5014735011 @default.
- W2893364020 creator A5035576547 @default.
- W2893364020 date "2019-01-01" @default.
- W2893364020 modified "2023-10-16" @default.
- W2893364020 title "Pharmacology of Oral Anticoagulants" @default.
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