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- W2893378314 abstract "The classification of hypertensive disorders of pregnancies (HDPs) especially pre-eclampsia (PET) vary according to different guidelines. Pregnancy characteristics, management and outcomes of women admitted with HDPs may differ by these definitions. To compare characteristics, management and outcomes associated with different definitions of PET and other HDPs. Dataset of 1972 women admitted with pre-eclampsia in a tertiary hospital in Canada from 2011 to 2016 was used for this study. Women were grouped into 8 groups: (1) chronic hypertension (CH), (2) gestational hypertension only; PET defined by (3) Hypertension and Hyperuricaemia only (4) Hypertension and accelerated hypertension only (5) Hypertension and proteinuria only (6) Hypertension and proteinuria only (7) PET defined by hypertension, proteinuria, and HELLP syndrome and (8) PET defined by hypertension, proteinuria, and either hyperuricaemia or accelerated hypertension. The demographic characteristics, management and adverse outcomes rates for the different groups of HDPs were compared. Majority of the women (32.3%) fell under group 8. Women in Group 1 were more likely to be older and multiparous but with the lowest rate of multiple pregnancy. Women in Group 2 were admitted at a later gestational age (GA) with the highest rate of smoking and had the least interventions (administration of antihypertensive, MgSO4 and antenatal corticosteroids, and caesarian delivery); consecutively group 7 had the earliest GA at admission, lowest smoking rate and most administrations with the highest rates of multiple pregnancy and adverse maternal and perinatal outcomes. The different definitions of HDPs were associated with differences with demographics, management and outcomes. Women in group 2 appeared to have the least adverse maternal and perinatal outcomes while women in group 7 (PET with both proteinuria and HELLP syndrome) had worse outcomes. These differences in outcomes by definitions may aid in directing the management of HDPs." @default.
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- W2893378314 date "2018-10-01" @default.
- W2893378314 modified "2023-10-18" @default.
- W2893378314 title "320. Pregnancy characteristics, management and outcomes according to different definitions of pre-eclampsia and other hypertensive disorders of pregnancy" @default.
- W2893378314 doi "https://doi.org/10.1016/j.preghy.2018.08.369" @default.
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