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- W2893396847 abstract "Aim: The risk of vitamin D binding protein (DBP) variations in chronic obstructive pulmonary disease (COPD) compared with non-COPD Thai males were investigated. Materials & methods: The rs7041 and rs4588 polymorphisms of the DBP gene and protein level were measured in 136 COPD and 68 non-COPD Thai males. Results: In the COPD group, GC1-1 gave increased forced expiratory volume at 1 s % predicted compared with GC1-2 but with no significant difference. Significantly lower average DBP serum levels were observed in COPD than non-COPD subjects. Positive correlation between serum DBP and forced expiratory volume at 1 s % predicted was observed in non-COPD subjects. Discussion & conclusion: DBP variations might be associated with risk factors in COPD caused by both inflammatory and vitamin D circulation processes." @default.
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- W2893396847 date "2018-09-01" @default.
- W2893396847 modified "2023-10-18" @default.
- W2893396847 title "Correlation of vitamin D binding protein gene polymorphism and protein levels in chronic obstructive pulmonary disease compared with non-chronic obstructive pulmonary disease subjects" @default.
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- W2893396847 doi "https://doi.org/10.2217/pme-2018-0005" @default.
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