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- W2893438302 abstract "Pancreatic endocrine cells, which are clustered in islets, regulate blood glucose stability and energy metabolism. The distinct cell types in islets, including insulin-secreting β cells, are differentiated from common endocrine progenitors during the embryonic stage. Immature endocrine cells expand via cell proliferation and mature during a long postnatal developmental period. However, the mechanisms underlying these processes are not clearly defined. Single-cell RNA-sequencing is a promising approach for the characterization of distinct cell populations and tracing cell lineage differentiation pathways. Here, we describe a method for the single-cell RNA-sequencing of isolated pancreatic β cells from embryonic, neonatal and postnatal pancreases." @default.
- W2893438302 created "2018-10-05" @default.
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- W2893438302 date "2018-09-30" @default.
- W2893438302 modified "2023-09-27" @default.
- W2893438302 title "Single-cell Transcriptomic Analyses of Mouse Pancreatic Endocrine Cells" @default.
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- W2893438302 doi "https://doi.org/10.3791/58000" @default.
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