FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893460045> ?p ?o ?g. }

• W2893460045 endingPage "2500" @default.
• W2893460045 startingPage "2490" @default.
• W2893460045 abstract "Chemical communication is fundamental for the operation of insect societies. Their diverse vocabulary of chemical signals requires a correspondingly diverse set of chemosensory receptors. Insect olfactory receptors (ORs) are the largest family of chemosensory receptors. The OR family is characterized by frequent expansions of subfamilies, in which duplicated ORs may adapt to detect new signals through positive selection on their amino acid sequence. Ants are an extreme example with ∼400 ORs per genome—the highest number in insects. Presumably, this reflects an increased complexity of chemical communication. Here, we examined gene duplications and positive selection on ant ORs. We reconstructed the hymenopteran OR gene tree, including five ant species, and inferred positive selection along every branch using the branch-site test, a total of 3326 tests. We find more positive selection in branches following species-specific duplications. We identified amino acid sites targeted by positive selection, and mapped them onto a structural model of insect ORs. Seventeen sites were under positive selection in six or more branches, forming two clusters on the extracellular side of the receptor, on either side of a cleft in the structure. This region was previously implicated in ligand activation, suggesting that the concentration of positively selected sites in this region is related to adaptive evolution of ligand binding sites or allosteric transmission of ligand activation. These results provide insights into the specific OR subfamilies and individual residues that facilitated adaptive evolution of olfactory functions, potentially explaining the elaboration of chemical signaling in ant societies." @default.
• W2893460045 created "2018-10-05" @default.
• W2893460045 creator A5004256381 @default.
• W2893460045 creator A5024573537 @default.
• W2893460045 creator A5026217419 @default.
• W2893460045 creator A5028460122 @default.
• W2893460045 date "2018-07-05" @default.
• W2893460045 modified "2023-10-14" @default.
• W2893460045 title "Neofunctionalization in Ligand Binding Sites of Ant Olfactory Receptors" @default.
• W2893460045 cites W1964511579 @default.
• W2893460045 cites W1969491977 @default.
• W2893460045 cites W1970384763 @default.
• W2893460045 cites W1972201383 @default.
• W2893460045 cites W1972745976 @default.
• W2893460045 cites W1982124226 @default.
• W2893460045 cites W1982583124 @default.
• W2893460045 cites W1985086335 @default.
• W2893460045 cites W1986678797 @default.
• W2893460045 cites W1993204833 @default.
• W2893460045 cites W2000815574 @default.
• W2893460045 cites W2004026630 @default.
• W2893460045 cites W2012172959 @default.
• W2893460045 cites W2051712246 @default.
• W2893460045 cites W2071202857 @default.
• W2893460045 cites W2072154669 @default.
• W2893460045 cites W2078997561 @default.
• W2893460045 cites W2082788644 @default.
• W2893460045 cites W2088196417 @default.
• W2893460045 cites W2097977090 @default.
• W2893460045 cites W2102502076 @default.
• W2893460045 cites W2111064199 @default.
• W2893460045 cites W2114772657 @default.
• W2893460045 cites W2115011276 @default.
• W2893460045 cites W2115643241 @default.
• W2893460045 cites W2121690059 @default.
• W2893460045 cites W2125127171 @default.
• W2893460045 cites W2125865118 @default.
• W2893460045 cites W2126556522 @default.
• W2893460045 cites W2127857503 @default.
• W2893460045 cites W2130909239 @default.
• W2893460045 cites W2150700711 @default.
• W2893460045 cites W2151529778 @default.
• W2893460045 cites W2152075687 @default.
• W2893460045 cites W2154099008 @default.
• W2893460045 cites W2168696662 @default.
• W2893460045 cites W2169411520 @default.
• W2893460045 cites W2201927605 @default.
• W2893460045 cites W4229487902 @default.
• W2893460045 doi "https://doi.org/10.1093/gbe/evy131" @default.
• W2893460045 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6161762" @default.
• W2893460045 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29982411" @default.
• W2893460045 hasPublicationYear "2018" @default.
• W2893460045 type Work @default.
• W2893460045 sameAs 2893460045 @default.
• W2893460045 citedByCount "15" @default.
• W2893460045 countsByYear W28934600452018 @default.
• W2893460045 countsByYear W28934600452019 @default.
• W2893460045 countsByYear W28934600452020 @default.
• W2893460045 countsByYear W28934600452021 @default.
• W2893460045 countsByYear W28934600452022 @default.
• W2893460045 countsByYear W28934600452023 @default.
• W2893460045 crossrefType "journal-article" @default.
• W2893460045 hasAuthorship W2893460045A5004256381 @default.
• W2893460045 hasAuthorship W2893460045A5024573537 @default.
• W2893460045 hasAuthorship W2893460045A5026217419 @default.
• W2893460045 hasAuthorship W2893460045A5028460122 @default.
• W2893460045 hasBestOaLocation W28934600451 @default.
• W2893460045 hasConcept C104317684 @default.
• W2893460045 hasConcept C107110972 @default.
• W2893460045 hasConcept C116569031 @default.
• W2893460045 hasConcept C141231307 @default.
• W2893460045 hasConcept C166342909 @default.
• W2893460045 hasConcept C170493617 @default.
• W2893460045 hasConcept C18903297 @default.
• W2893460045 hasConcept C2777612826 @default.
• W2893460045 hasConcept C2779980732 @default.
• W2893460045 hasConcept C54355233 @default.
• W2893460045 hasConcept C70721500 @default.
• W2893460045 hasConcept C7386963 @default.
• W2893460045 hasConcept C7602840 @default.
• W2893460045 hasConcept C78458016 @default.
• W2893460045 hasConcept C86803240 @default.
• W2893460045 hasConceptScore W2893460045C104317684 @default.
• W2893460045 hasConceptScore W2893460045C107110972 @default.
• W2893460045 hasConceptScore W2893460045C116569031 @default.
• W2893460045 hasConceptScore W2893460045C141231307 @default.
• W2893460045 hasConceptScore W2893460045C166342909 @default.
• W2893460045 hasConceptScore W2893460045C170493617 @default.
• W2893460045 hasConceptScore W2893460045C18903297 @default.
• W2893460045 hasConceptScore W2893460045C2777612826 @default.
• W2893460045 hasConceptScore W2893460045C2779980732 @default.
• W2893460045 hasConceptScore W2893460045C54355233 @default.
• W2893460045 hasConceptScore W2893460045C70721500 @default.
• W2893460045 hasConceptScore W2893460045C7386963 @default.
• W2893460045 hasConceptScore W2893460045C7602840 @default.
• W2893460045 hasConceptScore W2893460045C78458016 @default.
• W2893460045 hasConceptScore W2893460045C86803240 @default.
• W2893460045 hasIssue "9" @default.

• next