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• W2893515013 abstract "Extracts prepared from the eggs of frogs, particularly Xenopus species, have provided critical material for seminal studies of nuclear and chromosome dynamics over several decades. Their usefulness for these types of analyses lies in several important characteristics: stockpiled nuclear components, absence of endogenous DNA, and intact and functioning signaling networks. These factors have allowed detailed molecular analyses of many aspects of chromosome biology, including DNA replication, checkpoint signaling, epigenetic control, and chromosome condensation, cohesion, and segregation. In this introduction, the preparation and application of Xenopus egg extracts for the study of chromosomes and chromatin are described in detail." @default.
• W2893515013 created "2018-10-05" @default.
• W2893515013 creator A5058975499 @default.
• W2893515013 date "2018-08-27" @default.
• W2893515013 modified "2023-09-27" @default.
• W2893515013 title "Reconstituting Nuclear and Chromosome Dynamics Using <i>Xenopus</i> Extracts" @default.
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• W2893515013 doi "https://doi.org/10.1101/pdb.top097105" @default.
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