FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893519498> ?p ?o ?g. }

• W2893519498 endingPage "37s" @default.
• W2893519498 startingPage "37s" @default.
• W2893519498 abstract "Background: The tissue diagnosis of lymphoma and metastases is commonly obtained from affected lymph nodes. The lymph nodes chosen for biopsy are often the consequence of their appearance on ultrasound, which determines their risk of malignancy. Two frequently used percutaneous sampling techniques are core biopsy and fine needle aspiration (FNA). While core biopsy obtains a larger tissue sample and provides a degree of architectural information, FNA is considered less invasive and has the advantage of immediate confirmation of adequacy by the attending cytologist. Anecdotally, core biopsy is more commonly used when a lymph node is suspected of harboring neoplasia, however a feature of malignancy is hypercellularity, which theoretically should increase the diagnostic yield of FNA. Aim: The aim of this project was to compare the diagnostic capability of FNA and core biopsy in lymph nodes of different malignant potential, as defined by ultrasound, and determine if the radiologic appearance can guide clinicians in their choice of sampling technique. The project also reviewed the role of clinical experience in both the choice of sampling technique and diagnostic yield. Methods: Retrospective study of percutaneous lymph node biopsies performed at a large tertiary hospital between July 2016 and March 2018. The associated ultrasounds were reviewed and the lymph nodes were classified as high or low risk of malignancy by their sonographic appearance. The end point for analysis was the capacity for FNA or core biopsy to provide a definitive diagnosis. The diagnostic yield was then separately assessed for lymph nodes of high and low malignant potential. The effect of clinical experience on diagnostic yield was also examined, by comparing the outcomes of radiology consultants and radiology trainees. Results: 296 lymph node biopsies were reviewed and statistical analysis was performed using logistic regression analysis. Core biopsy, in comparison with FNA, was used twice as often in lymph nodes of high malignant potential, supporting the aforementioned anecdotal evidence. Core biopsy demonstrated superior diagnostic yield in comparison with FNA, providing a diagnostic sample 45% ( P = 0.313) more often in low-risk lymph nodes and 209% ( P = < 0.05) more often in high-risk lymph nodes. Consultant radiologists used FNA 81% more often than core biopsy in lymph nodes of high malignant potential, while radiology trainees used core biopsy 104% more often than FNA in the same group. In high-risk lymph nodes, trainees were 117% ( P = 0.105) more likely to obtain a diagnostic sample than consultants. Conclusion: Core biopsy is superior to FNA in the tissue sampling of lymph nodes regardless of ultrasound determined risk of malignancy. Biopsies obtained by radiology trainees provided a diagnosis twice as often as those obtained by radiology consultants. This appeared to be the consequence of consultant preference for FNA over core biopsy." @default.
• W2893519498 created "2018-10-05" @default.
• W2893519498 creator A5002229605 @default.
• W2893519498 creator A5061694011 @default.
• W2893519498 creator A5076352483 @default.
• W2893519498 date "2018-10-01" @default.
• W2893519498 modified "2023-09-27" @default.
• W2893519498 title "Core Biopsy and FNA: A Comparison of Diagnostic Yield in Lymph Nodes of Different Ultrasound Determined Malignant Potential" @default.
• W2893519498 doi "https://doi.org/10.1200/jgo.18.66100" @default.
• W2893519498 hasPublicationYear "2018" @default.
• W2893519498 type Work @default.
• W2893519498 sameAs 2893519498 @default.
• W2893519498 citedByCount "0" @default.
• W2893519498 crossrefType "journal-article" @default.
• W2893519498 hasAuthorship W2893519498A5002229605 @default.
• W2893519498 hasAuthorship W2893519498A5061694011 @default.
• W2893519498 hasAuthorship W2893519498A5076352483 @default.
• W2893519498 hasBestOaLocation W28935194981 @default.
• W2893519498 hasConcept C106131492 @default.
• W2893519498 hasConcept C126838900 @default.
• W2893519498 hasConcept C140779682 @default.
• W2893519498 hasConcept C142724271 @default.
• W2893519498 hasConcept C2775934546 @default.
• W2893519498 hasConcept C2776170712 @default.
• W2893519498 hasConcept C2779399171 @default.
• W2893519498 hasConcept C2779720271 @default.
• W2893519498 hasConcept C2780813298 @default.
• W2893519498 hasConcept C2780849966 @default.
• W2893519498 hasConcept C31972630 @default.
• W2893519498 hasConcept C41008148 @default.
• W2893519498 hasConcept C71924100 @default.
• W2893519498 hasConceptScore W2893519498C106131492 @default.
• W2893519498 hasConceptScore W2893519498C126838900 @default.
• W2893519498 hasConceptScore W2893519498C140779682 @default.
• W2893519498 hasConceptScore W2893519498C142724271 @default.
• W2893519498 hasConceptScore W2893519498C2775934546 @default.
• W2893519498 hasConceptScore W2893519498C2776170712 @default.
• W2893519498 hasConceptScore W2893519498C2779399171 @default.
• W2893519498 hasConceptScore W2893519498C2779720271 @default.
• W2893519498 hasConceptScore W2893519498C2780813298 @default.
• W2893519498 hasConceptScore W2893519498C2780849966 @default.
• W2893519498 hasConceptScore W2893519498C31972630 @default.
• W2893519498 hasConceptScore W2893519498C41008148 @default.
• W2893519498 hasConceptScore W2893519498C71924100 @default.
• W2893519498 hasIssue "Supplement 2" @default.
• W2893519498 hasLocation W28935194981 @default.
• W2893519498 hasOpenAccess W2893519498 @default.
• W2893519498 hasPrimaryLocation W28935194981 @default.
• W2893519498 hasRelatedWork W1511885230 @default.
• W2893519498 hasRelatedWork W1897659454 @default.
• W2893519498 hasRelatedWork W1991221913 @default.
• W2893519498 hasRelatedWork W2038155791 @default.
• W2893519498 hasRelatedWork W2091944169 @default.
• W2893519498 hasRelatedWork W2101143871 @default.
• W2893519498 hasRelatedWork W2126658009 @default.
• W2893519498 hasRelatedWork W2415233600 @default.
• W2893519498 hasRelatedWork W2419052398 @default.
• W2893519498 hasRelatedWork W3097381871 @default.
• W2893519498 hasVolume "4" @default.
• W2893519498 isParatext "false" @default.
• W2893519498 isRetracted "false" @default.
• W2893519498 magId "2893519498" @default.
• W2893519498 workType "article" @default.