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• W2893522241 endingPage "12641" @default.
• W2893522241 startingPage "12635" @default.
• W2893522241 abstract "Microemulsions (MEs) containing deep eutectic solvents (DESs) and water in the inner phase for use in transdermal delivery of poorly soluble drugs were prepared using a mixture of polyoxyethylene sorbitan monooleate (Tween-80) and sorbitan laurate (Span-20) as surfactants. We investigated the effects of the ratios of surfactant (Tween-80/Span-20) and solvents (DES components/water) on the ME structure determined by the analysis of small-angle X-ray scattering profiles with the core–corona model. Tween-80 with an unsaturated long alkyl chain induced a structural transition of MEs from a sphere to a cylinder. DESs caused the aggregation of surfactants due to the solvophobic interactions between DESs and the alkyl chains of surfactants. Transmittance electron microscopy images of MEs indicated the presence of aggregates of the dispersed ME particles with each shape." @default.
• W2893522241 created "2018-10-05" @default.
• W2893522241 creator A5013056242 @default.
• W2893522241 creator A5019395496 @default.
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• W2893522241 date "2018-09-25" @default.
• W2893522241 modified "2023-10-07" @default.
• W2893522241 title "Deep Eutectic Solvent-Induced Structural Transition of Microemulsions Explored with Small-Angle X-ray Scattering" @default.
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• W2893522241 doi "https://doi.org/10.1021/acs.langmuir.8b02565" @default.
• W2893522241 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30251861" @default.
• W2893522241 hasPublicationYear "2018" @default.
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