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- W2893534477 abstract "Abstract Chitosan is an extremely valuable biopolymer and is usually obtained as a byproduct from the shells of crustaceans. In the current work, chitosan is obtained from an herbal source ( Ganoderma lucidum spore powder (GLSP)) for the first time. To show this, both standard (thermochemical deacetylation, (TCD)) and emerging (ultrasound-assisted deacetylation (USAD)) methods of chitosan preparation were used. The obtained chitosan was characterized by elemental analysis, XRD (X-ray diffraction), FT-IR (Fourier transform infrared spectroscopy) and thermogravimetric measurements. The process resulted in chitosan possessing comparable values of DD, [η] and $$,overline{{rm{Mv}}}$$ <mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML> <mml:mspace /> <mml:mover> <mml:mrow> <mml:mi>Mv</mml:mi> </mml:mrow> <mml:mrow> <mml:mo>¯</mml:mo> </mml:mrow> </mml:mover> </mml:math> to the commercial product. Chitosan obtained via both processes (TCD and USAD) displayed excellent biocompatibility; although the USAD prepared biopolymer exhibited significantly improved fibroblast (L929 cell) viability and enhanced antibacterial zones for both Escherichia coli ( E. coli ) and Staphylococcus aureus ( S. aureus ). The findings of new herbal chitosan mark key developments of natural biomaterials; marking a potential shift from conventional sea-based organisms." @default.
- W2893534477 created "2018-10-05" @default.
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- W2893534477 date "2018-10-02" @default.
- W2893534477 modified "2023-10-12" @default.
- W2893534477 title "Synthesis and Evaluation of Herbal Chitosan from Ganoderma Lucidum Spore Powder for Biomedical Applications" @default.
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- W2893534477 doi "https://doi.org/10.1038/s41598-018-33088-5" @default.
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