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- W2893539866 abstract "Objectives: The aim of this study was to verify if there are poly (methyl methacrylate) (PMMA) absorptionand releasing of nystatin (NYS) and fluconazole (FLZ) after simulated treatment of oral candidosis. Materialsand methods: Specimens (30 × 25 × 5 mm) prepared with PMMA polymerized by hot water bath or microwaveenergy were immersed into NYS (3.12 μg/mL), FLZ (2.56 μg/mL) or deionized water (control) during14 days at 35 ± 2 °C. After treatment simulation, specimens were immersed into distilled water during 3, 7, 10and 14 days. The immersion liquid was changed after each analysis. Higher performance liquid chromatographywas used in order to detect antifungal compounds. In order to determine if there was surface depositionof drugs on PMMA resin, specimens were analyzed with electronic microscopy (SEM). Results: None of theantifungal agents was released from the PMMA resins. Conclusion: Within the limitations of this study, itcould be concluded that PMMA resins had no drug absorption with posterior release." @default.
- W2893539866 created "2018-10-05" @default.
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- W2893539866 date "2011-11-28" @default.
- W2893539866 modified "2023-09-25" @default.
- W2893539866 title "POLY (METHYL METHACRYLATE) ABSORPTION ANDRELEASING OF NYSTATIN AND FLUCONAZOLE" @default.
- W2893539866 doi "https://doi.org/10.7213/aor.v7i3.23095" @default.
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