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• W2893548416 abstract "Background: Enterobacteriacea are able to cause urinary tract infections, and Escherichia coli (E. coli) and Klebsiella pneumonia are the most frequently isolated pathogens from urinary samples. Untreated urinary tract infections can cause upper and lower urinary tract infections. These are among the most common infectious diseases in children. Septicemia and antibiotic resistance of urinary bacteria are the most important concerns in the developed and developing countries. One of the solutions for antibiotic resistance is herbal therapy, which as a branch of traditional medicine, has served an important role in disease treatment during the past century. The advantages of herbal therapy include minimum complications, cost-effectiveness, and high popularity. Herbalism has had a significant role in disease treatment. In this study, the antimicrobial effect of Pistacia atlantica was investigated in 2014. Methods: This cross-sectional study was performed on 150 patients with positive urinary cultures in Imam Ali Hospital of Zahedan, Iran. All the cases of positive culture during three months were investigated. Extraction of ethanolic extract of Pistacia atlantica was performed by a rotary device. Firstly, the antibacterial effect of Pistacia atlantica was assessed with the disk diffusion method at four concentrations, and then for bacteria that were sensitive to this extract, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined. Antibacterial effect of Pistacia atlantica ethanolic extract on urinary tract infection was compared with some conventional antibiotics, and the data were analyzed using Chi-square test in SPSS. Results: E. coli, Klebsiella pneumonia, and Staphylococcus aureus were isolated from urinary samples. Ethanolic extract of Pistacia atlantica created maximum non-growth halo at the concentration of 100 mg/mL, but at the 12.5 and 25 mg/mL concentrations the extract created minimum non-growth halo, indicating the bacteria were resistant in these concentrations. Overall, 27 of 150 bacteria showed sensitivity to Pistacia atlantica at the 50 and 100 mg/mL concentrations. The most sensitive bacteria to this extract were E. coli and Staphylococcus aureus, respectively. Conclusions: The results presented the antibacterial effect of ethanolic extract of Pistacia atlantica is higher at higher concentrations." @default.
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• W2893548416 date "2018-09-30" @default.
• W2893548416 modified "2023-10-14" @default.
• W2893548416 title "Comparison of Antimicrobial Effect of Pistacia atlantica with Antibiotics in Urinary Tract Infection" @default.
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• W2893548416 doi "https://doi.org/10.5812/zjrms.63589" @default.
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