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- W2893551963 endingPage "308" @default.
- W2893551963 startingPage "285" @default.
- W2893551963 abstract "Maintenance of a homeostatic body core temperature is a critical brain function accomplished by a central neural network. This orchestrates a complex behavioral and autonomic repertoire in response to environmental temperature challenges or declining energy homeostasis and in support of immune responses and many behavioral states. This review summarizes the anatomical, neurotransmitter, and functional relationships within the central neural network that controls the principal thermoeffectors: cutaneous vasoconstriction regulating heat loss and shivering and brown adipose tissue for heat production. The core thermoregulatory network regulating these thermoeffectors consists of parallel but distinct central efferent pathways that share a common peripheral thermal sensory input. Delineating the neural circuit mechanism underlying central thermoregulation provides a useful platform for exploring its functional organization, elucidating the molecular underpinnings of its neuronal interactions, and discovering novel therapeutic approaches to modulating body temperature and energy homeostasis." @default.
- W2893551963 created "2018-10-05" @default.
- W2893551963 creator A5016084389 @default.
- W2893551963 creator A5078989242 @default.
- W2893551963 date "2019-02-10" @default.
- W2893551963 modified "2023-10-09" @default.
- W2893551963 title "Central Mechanisms for Thermoregulation" @default.
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